Determination of free valproic acid : evaluation of the centrifree system and comparison between high-performance liquid chromatography and enzyme immunoassay

Valproic Acid (VPA) is an important drug for the treatment of several types of seizures because it has a wide spectrum of activity. Since VPA has an unusual nonlinear binding characteristic and a wide interindividual variation, monitoring of its free concentration can be helpful in patient managemen...

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Veröffentlicht in:	Therapeutic drug monitoring 1992-12, Vol.14 (6), p.513-521
Hauptverfasser:	HUA LIU, MONTOYA, J. L, FORMAN, L. J, EGGERS, C. M, BARHAM, C. F, DELGADO, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anticonvulsants - blood Biological and medical sciences Chromatography, High Pressure Liquid - methods Evaluation Studies as Topic General pharmacology Humans Immunoenzyme Techniques Medical sciences Pharmacology. Drug treatments Ultrafiltration Valproic Acid - blood
Online-Zugang:	Volltext
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