Intracellular distribution of p300 and its differential recruitment to aggresomes in breast cancer

It has been recently suggested that p300 cytoplasmic redistribution and degradation are important for controlling the availability and activity of the protein as a transcriptional coactivator. As a step towards determining the functional relevance of p300 intracellular redistribution in mammary canc...

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Veröffentlicht in:	Experimental and molecular pathology 2010-04, Vol.88 (2), p.256-264
Hauptverfasser:	FERMENTO, Maria E, GANDINI, Norberto A, LANG, Cecilia A, PEREZ, Juan E, MATURI, Horacio V, CURINO, Alejandro C, FACCHINETTI, Maria M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Animals Biological and medical sciences Blotting, Western Breast - metabolism Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Line, Tumor Cytoplasm - metabolism Cytoplasm - pathology E1A-Associated p300 Protein - genetics E1A-Associated p300 Protein - metabolism Female Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Inclusion Bodies - metabolism Inclusion Bodies - pathology Investigative techniques, diagnostic techniques (general aspects) Mammary gland diseases Mammary Glands, Animal - metabolism Mammary Neoplasms, Animal - genetics Medical sciences Mice Mice, Transgenic Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Proteasome Endopeptidase Complex - genetics Proteasome Endopeptidase Complex - metabolism Reference Values Transcription, Genetic Tumors Ubiquitin - metabolism Vimentin - metabolism
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