Catalpol inhibits apoptosis in hydrogen peroxide-induced endothelium by activating the PI3K/Akt signaling pathway and modulating expression of Bcl-2 and Bax

Catalpol, an iridoid glucoside found in the root of Rehmannia glutinosa Libosch, has been demonstrated to reduce apoptosis in neuronal cell lines. Recent data suggests that catalpol also exerts anti-apoptotic effects on other cell types. The aim of the present study was to investigate whether catalp...

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Veröffentlicht in:European journal of pharmacology 2010-02, Vol.628 (1), p.155-163
Hauptverfasser: Hu, Lingai, Sun, Yukun, Hu, Jian
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Sprache:eng
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