A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease
Brain injury is the most common long-term complication of congenital heart disease requiring surgery during infancy. It is clear that the youngest patients undergoing cardiac surgery, primarily neonates and young infants, are at the greatest risk for brain injury. Developmental anomalies sustained e...
Gespeichert in:
| Veröffentlicht in: | Pediatrics (Evanston) 2010-04, Vol.125 (4), p.e818-e827 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e827 |
|---|---|
| container_issue | 4 |
| container_start_page | e818 |
| container_title | Pediatrics (Evanston) |
| container_volume | 125 |
| creator | Snookes, Suzanne H Gunn, Julia K Eldridge, Bev J Donath, Susan M Hunt, Rod W Galea, Mary P Shekerdemian, Lara |
| description | Brain injury is the most common long-term complication of congenital heart disease requiring surgery during infancy. It is clear that the youngest patients undergoing cardiac surgery, primarily neonates and young infants, are at the greatest risk for brain injury. Developmental anomalies sustained early in life have lifelong repercussions.
We conducted a systematic review to examine longitudinal studies of cognitive and/or motor outcome after cardiac surgery during early infancy.
Electronic searches were performed in Medline, the Cumulative Index to Nursing and Allied Health Literature (Cinahl), and Embase (1998-2008). The search strategy yielded 327 articles, of which 65 were reviewed. Eight cohorts provided prospective data regarding the cognitive and/or motor outcome of infants who had undergone surgery for congenital heart disease before 6 months of age. Two authors, Ms Snookes and Dr Gunn, independently extracted data and presented results according to 3 subgroups for age of follow-up: early development (1 to 5 to 17 years). Weighted analysis was undertaken to pool the results of studies when appropriate.
All of the identified studies reported results of the Bayley Scales of Infant Development for children younger than the age of 3. Outcome data as reported by the Bayley Scales were combined for infants assessed at 1 year of age, revealing a weighted mean Mental Development Index of 90.3 (95% confidence interval: 88.9-91.6) and Psychomotor Development Index of 78.1 (95% confidence interval: 76.4-79.7). Additional analysis was limited by a lack of data at preschool and school age.
With this review we identified a limited number of prospective studies that systematically addressed outcome in patients at the highest risk. These studies consistently revealed cognitive and motor delay in children after cardiac surgery during early infancy. Additional investigation is required to ascertain the consequences of such impairment during later childhood and into adult life. |
| doi_str_mv | 10.1542/peds.2009-1959 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733847620</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733847620</sourcerecordid><originalsourceid>FETCH-LOGICAL-c387t-1e65a6f39a39fa84848cb8ce5ba7dff2425e059a364157b2e825833be3b2115d3</originalsourceid><addsrcrecordid>eNpdkD1PwzAQhi0EoqWwMiKLhSnFH3HjjFXFl1SJBWbLcc4lVRIX2ynKv8dVgQHdcMP73KvTg9A1JXMqcna_gzrMGSFlRktRnqApJaXMclaIUzQlhNMsJ0RM0EUIW0JILgp2jiaMME6pZFNUL3EYQ4ROx8ZgD_sGvrCzuHPReaz7Ghu36ZvY7AG7IRrXQcDaRvAYtG9HHAa_AT9im3Dj-g0kWLf4I6UR100AHeASnVndBrj62TP0_vjwtnrO1q9PL6vlOjNcFjGjsBB6YXmpeWm1zNOYShoQlS5qa1nOBBCR0kVORVExkExIzivgFaNU1HyG7o69O-8-BwhRdU0w0La6BzcEVXAu82LBSCJv_5FbN_g-PacYk1zQsqQJmh8h410IHqza-abTflSUqIN9dbCvDvbVwX46uPlpHaoO6j_8Vzf_BmmWgSQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>228351991</pqid></control><display><type>article</type><title>A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Snookes, Suzanne H ; Gunn, Julia K ; Eldridge, Bev J ; Donath, Susan M ; Hunt, Rod W ; Galea, Mary P ; Shekerdemian, Lara</creator><creatorcontrib>Snookes, Suzanne H ; Gunn, Julia K ; Eldridge, Bev J ; Donath, Susan M ; Hunt, Rod W ; Galea, Mary P ; Shekerdemian, Lara</creatorcontrib><description>Brain injury is the most common long-term complication of congenital heart disease requiring surgery during infancy. It is clear that the youngest patients undergoing cardiac surgery, primarily neonates and young infants, are at the greatest risk for brain injury. Developmental anomalies sustained early in life have lifelong repercussions.
We conducted a systematic review to examine longitudinal studies of cognitive and/or motor outcome after cardiac surgery during early infancy.
Electronic searches were performed in Medline, the Cumulative Index to Nursing and Allied Health Literature (Cinahl), and Embase (1998-2008). The search strategy yielded 327 articles, of which 65 were reviewed. Eight cohorts provided prospective data regarding the cognitive and/or motor outcome of infants who had undergone surgery for congenital heart disease before 6 months of age. Two authors, Ms Snookes and Dr Gunn, independently extracted data and presented results according to 3 subgroups for age of follow-up: early development (1 to <3 years); preschool age (3-5 years); and school age (>5 to 17 years). Weighted analysis was undertaken to pool the results of studies when appropriate.
All of the identified studies reported results of the Bayley Scales of Infant Development for children younger than the age of 3. Outcome data as reported by the Bayley Scales were combined for infants assessed at 1 year of age, revealing a weighted mean Mental Development Index of 90.3 (95% confidence interval: 88.9-91.6) and Psychomotor Development Index of 78.1 (95% confidence interval: 76.4-79.7). Additional analysis was limited by a lack of data at preschool and school age.
With this review we identified a limited number of prospective studies that systematically addressed outcome in patients at the highest risk. These studies consistently revealed cognitive and motor delay in children after cardiac surgery during early infancy. Additional investigation is required to ascertain the consequences of such impairment during later childhood and into adult life.</description><identifier>ISSN: 0031-4005</identifier><identifier>EISSN: 1098-4275</identifier><identifier>DOI: 10.1542/peds.2009-1959</identifier><identifier>PMID: 20231182</identifier><identifier>CODEN: PEDIAU</identifier><language>eng</language><publisher>United States: American Academy of Pediatrics</publisher><subject>Age Factors ; Babies ; Cardiovascular disease ; Cognition & reasoning ; Cognition Disorders - diagnosis ; Cognition Disorders - etiology ; Cognition Disorders - physiopathology ; Congenital diseases ; Heart Defects, Congenital - complications ; Heart Defects, Congenital - surgery ; Heart surgery ; Humans ; Infant, Newborn ; Longitudinal Studies ; Motor ability ; Motor Skills Disorders - diagnosis ; Motor Skills Disorders - etiology ; Motor Skills Disorders - physiopathology ; Pediatrics ; Postoperative Complications - diagnosis ; Postoperative Complications - etiology ; Postoperative Complications - physiopathology ; Systematic review ; Treatment Outcome</subject><ispartof>Pediatrics (Evanston), 2010-04, Vol.125 (4), p.e818-e827</ispartof><rights>Copyright American Academy of Pediatrics Apr 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-1e65a6f39a39fa84848cb8ce5ba7dff2425e059a364157b2e825833be3b2115d3</citedby><cites>FETCH-LOGICAL-c387t-1e65a6f39a39fa84848cb8ce5ba7dff2425e059a364157b2e825833be3b2115d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20231182$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Snookes, Suzanne H</creatorcontrib><creatorcontrib>Gunn, Julia K</creatorcontrib><creatorcontrib>Eldridge, Bev J</creatorcontrib><creatorcontrib>Donath, Susan M</creatorcontrib><creatorcontrib>Hunt, Rod W</creatorcontrib><creatorcontrib>Galea, Mary P</creatorcontrib><creatorcontrib>Shekerdemian, Lara</creatorcontrib><title>A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease</title><title>Pediatrics (Evanston)</title><addtitle>Pediatrics</addtitle><description>Brain injury is the most common long-term complication of congenital heart disease requiring surgery during infancy. It is clear that the youngest patients undergoing cardiac surgery, primarily neonates and young infants, are at the greatest risk for brain injury. Developmental anomalies sustained early in life have lifelong repercussions.
We conducted a systematic review to examine longitudinal studies of cognitive and/or motor outcome after cardiac surgery during early infancy.
Electronic searches were performed in Medline, the Cumulative Index to Nursing and Allied Health Literature (Cinahl), and Embase (1998-2008). The search strategy yielded 327 articles, of which 65 were reviewed. Eight cohorts provided prospective data regarding the cognitive and/or motor outcome of infants who had undergone surgery for congenital heart disease before 6 months of age. Two authors, Ms Snookes and Dr Gunn, independently extracted data and presented results according to 3 subgroups for age of follow-up: early development (1 to <3 years); preschool age (3-5 years); and school age (>5 to 17 years). Weighted analysis was undertaken to pool the results of studies when appropriate.
All of the identified studies reported results of the Bayley Scales of Infant Development for children younger than the age of 3. Outcome data as reported by the Bayley Scales were combined for infants assessed at 1 year of age, revealing a weighted mean Mental Development Index of 90.3 (95% confidence interval: 88.9-91.6) and Psychomotor Development Index of 78.1 (95% confidence interval: 76.4-79.7). Additional analysis was limited by a lack of data at preschool and school age.
With this review we identified a limited number of prospective studies that systematically addressed outcome in patients at the highest risk. These studies consistently revealed cognitive and motor delay in children after cardiac surgery during early infancy. Additional investigation is required to ascertain the consequences of such impairment during later childhood and into adult life.</description><subject>Age Factors</subject><subject>Babies</subject><subject>Cardiovascular disease</subject><subject>Cognition & reasoning</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - etiology</subject><subject>Cognition Disorders - physiopathology</subject><subject>Congenital diseases</subject><subject>Heart Defects, Congenital - complications</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Longitudinal Studies</subject><subject>Motor ability</subject><subject>Motor Skills Disorders - diagnosis</subject><subject>Motor Skills Disorders - etiology</subject><subject>Motor Skills Disorders - physiopathology</subject><subject>Pediatrics</subject><subject>Postoperative Complications - diagnosis</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - physiopathology</subject><subject>Systematic review</subject><subject>Treatment Outcome</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkD1PwzAQhi0EoqWwMiKLhSnFH3HjjFXFl1SJBWbLcc4lVRIX2ynKv8dVgQHdcMP73KvTg9A1JXMqcna_gzrMGSFlRktRnqApJaXMclaIUzQlhNMsJ0RM0EUIW0JILgp2jiaMME6pZFNUL3EYQ4ROx8ZgD_sGvrCzuHPReaz7Ghu36ZvY7AG7IRrXQcDaRvAYtG9HHAa_AT9im3Dj-g0kWLf4I6UR100AHeASnVndBrj62TP0_vjwtnrO1q9PL6vlOjNcFjGjsBB6YXmpeWm1zNOYShoQlS5qa1nOBBCR0kVORVExkExIzivgFaNU1HyG7o69O-8-BwhRdU0w0La6BzcEVXAu82LBSCJv_5FbN_g-PacYk1zQsqQJmh8h410IHqza-abTflSUqIN9dbCvDvbVwX46uPlpHaoO6j_8Vzf_BmmWgSQ</recordid><startdate>201004</startdate><enddate>201004</enddate><creator>Snookes, Suzanne H</creator><creator>Gunn, Julia K</creator><creator>Eldridge, Bev J</creator><creator>Donath, Susan M</creator><creator>Hunt, Rod W</creator><creator>Galea, Mary P</creator><creator>Shekerdemian, Lara</creator><general>American Academy of Pediatrics</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>201004</creationdate><title>A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease</title><author>Snookes, Suzanne H ; Gunn, Julia K ; Eldridge, Bev J ; Donath, Susan M ; Hunt, Rod W ; Galea, Mary P ; Shekerdemian, Lara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-1e65a6f39a39fa84848cb8ce5ba7dff2425e059a364157b2e825833be3b2115d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Age Factors</topic><topic>Babies</topic><topic>Cardiovascular disease</topic><topic>Cognition & reasoning</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognition Disorders - etiology</topic><topic>Cognition Disorders - physiopathology</topic><topic>Congenital diseases</topic><topic>Heart Defects, Congenital - complications</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Longitudinal Studies</topic><topic>Motor ability</topic><topic>Motor Skills Disorders - diagnosis</topic><topic>Motor Skills Disorders - etiology</topic><topic>Motor Skills Disorders - physiopathology</topic><topic>Pediatrics</topic><topic>Postoperative Complications - diagnosis</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - physiopathology</topic><topic>Systematic review</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Snookes, Suzanne H</creatorcontrib><creatorcontrib>Gunn, Julia K</creatorcontrib><creatorcontrib>Eldridge, Bev J</creatorcontrib><creatorcontrib>Donath, Susan M</creatorcontrib><creatorcontrib>Hunt, Rod W</creatorcontrib><creatorcontrib>Galea, Mary P</creatorcontrib><creatorcontrib>Shekerdemian, Lara</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatrics (Evanston)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Snookes, Suzanne H</au><au>Gunn, Julia K</au><au>Eldridge, Bev J</au><au>Donath, Susan M</au><au>Hunt, Rod W</au><au>Galea, Mary P</au><au>Shekerdemian, Lara</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease</atitle><jtitle>Pediatrics (Evanston)</jtitle><addtitle>Pediatrics</addtitle><date>2010-04</date><risdate>2010</risdate><volume>125</volume><issue>4</issue><spage>e818</spage><epage>e827</epage><pages>e818-e827</pages><issn>0031-4005</issn><eissn>1098-4275</eissn><coden>PEDIAU</coden><abstract>Brain injury is the most common long-term complication of congenital heart disease requiring surgery during infancy. It is clear that the youngest patients undergoing cardiac surgery, primarily neonates and young infants, are at the greatest risk for brain injury. Developmental anomalies sustained early in life have lifelong repercussions.
We conducted a systematic review to examine longitudinal studies of cognitive and/or motor outcome after cardiac surgery during early infancy.
Electronic searches were performed in Medline, the Cumulative Index to Nursing and Allied Health Literature (Cinahl), and Embase (1998-2008). The search strategy yielded 327 articles, of which 65 were reviewed. Eight cohorts provided prospective data regarding the cognitive and/or motor outcome of infants who had undergone surgery for congenital heart disease before 6 months of age. Two authors, Ms Snookes and Dr Gunn, independently extracted data and presented results according to 3 subgroups for age of follow-up: early development (1 to <3 years); preschool age (3-5 years); and school age (>5 to 17 years). Weighted analysis was undertaken to pool the results of studies when appropriate.
All of the identified studies reported results of the Bayley Scales of Infant Development for children younger than the age of 3. Outcome data as reported by the Bayley Scales were combined for infants assessed at 1 year of age, revealing a weighted mean Mental Development Index of 90.3 (95% confidence interval: 88.9-91.6) and Psychomotor Development Index of 78.1 (95% confidence interval: 76.4-79.7). Additional analysis was limited by a lack of data at preschool and school age.
With this review we identified a limited number of prospective studies that systematically addressed outcome in patients at the highest risk. These studies consistently revealed cognitive and motor delay in children after cardiac surgery during early infancy. Additional investigation is required to ascertain the consequences of such impairment during later childhood and into adult life.</abstract><cop>United States</cop><pub>American Academy of Pediatrics</pub><pmid>20231182</pmid><doi>10.1542/peds.2009-1959</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0031-4005 |
| ispartof | Pediatrics (Evanston), 2010-04, Vol.125 (4), p.e818-e827 |
| issn | 0031-4005 1098-4275 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_733847620 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Age Factors Babies Cardiovascular disease Cognition & reasoning Cognition Disorders - diagnosis Cognition Disorders - etiology Cognition Disorders - physiopathology Congenital diseases Heart Defects, Congenital - complications Heart Defects, Congenital - surgery Heart surgery Humans Infant, Newborn Longitudinal Studies Motor ability Motor Skills Disorders - diagnosis Motor Skills Disorders - etiology Motor Skills Disorders - physiopathology Pediatrics Postoperative Complications - diagnosis Postoperative Complications - etiology Postoperative Complications - physiopathology Systematic review Treatment Outcome |
| title | A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T21%3A11%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20systematic%20review%20of%20motor%20and%20cognitive%20outcomes%20after%20early%20surgery%20for%20congenital%20heart%20disease&rft.jtitle=Pediatrics%20(Evanston)&rft.au=Snookes,%20Suzanne%20H&rft.date=2010-04&rft.volume=125&rft.issue=4&rft.spage=e818&rft.epage=e827&rft.pages=e818-e827&rft.issn=0031-4005&rft.eissn=1098-4275&rft.coden=PEDIAU&rft_id=info:doi/10.1542/peds.2009-1959&rft_dat=%3Cproquest_cross%3E733847620%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=228351991&rft_id=info:pmid/20231182&rfr_iscdi=true |