Protease Imaging of Human Atheromata Captures Molecular Information of Atherosclerosis, Complementing Anatomic Imaging

OBJECTIVE—There is hope that molecular imaging can identify vulnerable atherosclerotic plaques. However, there is a paucity of clinical translational data to guide the future development of this field. Here, we cross-correlate cathepsin-B or matrix metalloproteinase-2/-9 molecular optical imaging da...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2010-03, Vol.30 (3), p.449-456
Hauptverfasser:	Kim, Dong-Eog, Kim, Jeong-Yeon, Schellingerhout, Dawid, Kim, Eo-Jin, Kim, Hyang Kyoung, Lee, Seulki, Kim, Kwangmeyung, Kwon, Ick Chan, Shon, Soo-Min, Jeong, Sang-Wuk, Im, So-Hyang, Lee, Dong Kun, Lee, Myoung Mook, Kim, Geun-Eun
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood. Blood coagulation. Reticuloendothelial system Cardiology. Vascular system Carotid Arteries - diagnostic imaging Carotid Arteries - pathology Carotid Stenosis - diagnosis Carotid Stenosis - pathology Carotid Stenosis - therapy Cathepsin B Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Endarterectomy, Carotid Female Fluorescent Dyes Humans Male Matrix Metalloproteinase 2 Matrix Metalloproteinase 9 Medical sciences Molecular Imaging - methods Peptide Hydrolases Pharmacology. Drug treatments Prospective Studies Retrospective Studies Stents Ultrasonography
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