A 1-year longitudinal study of psychological morbidity after miscarriage
Objective To examine the 1-year longitudinal course of psychological outcomes after miscarriage. Design Longitudinal observational study. Setting University-affiliated teaching hospital. Patient(s) 280 miscarrying women and 150 nonpregnant women. Intervention(s) Psychological outcomes were assessed...
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| Veröffentlicht in: | Fertility and sterility 2010-04, Vol.93 (6), p.1966-1975 |
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| container_end_page | 1975 |
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| container_issue | 6 |
| container_start_page | 1966 |
| container_title | Fertility and sterility |
| container_volume | 93 |
| creator | Lok, Ingrid Hung, M.D Yip, Alexander Shing-Kai, M.D Lee, Dominic Tak-Sing, M.D Sahota, Daljit, Ph.D Chung, Tony Kwok-Hung, M.D |
| description | Objective To examine the 1-year longitudinal course of psychological outcomes after miscarriage. Design Longitudinal observational study. Setting University-affiliated teaching hospital. Patient(s) 280 miscarrying women and 150 nonpregnant women. Intervention(s) Psychological outcomes were assessed using the 12-item General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) immediately, 3 months, 6 months, and 12 months after miscarriage. Main Outcome Measure(s) Scores on GHQ-12 and BDI. Result(s) Half (55%) of the miscarrying women scored high (≥4) on the GHQ-12 immediately, 25% at 3 months; 17.8% at 6 months, and 10.8% at 1 year after miscarriage; 26.8% of the patients scored high on the BDI (≥12) immediately, 18.4% at 3 months, 16.4% at 6 months, and 9.3% at 1 year after miscarriage. Patients who were initially more distressed continued to score higher on both the GHQ-12 and the BDI along the 1-year course when compared with those who were initially less distressed. When compared with the nonpregnant controls, the miscarrying women scored statistically significantly higher on the GHQ-12 and BDI; the differences became not statistically significant only 1 year after miscarriage. Conclusion(s) A statistically significant proportion of patients reported psychological morbidity shortly after miscarriage, but their level of distress reduced over time until they were comparable with the controls 1 year later. Patients who were initially more distressed continued to be throughout the 1-year course. |
| doi_str_mv | 10.1016/j.fertnstert.2008.12.048 |
| format | Article |
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Design Longitudinal observational study. Setting University-affiliated teaching hospital. Patient(s) 280 miscarrying women and 150 nonpregnant women. Intervention(s) Psychological outcomes were assessed using the 12-item General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) immediately, 3 months, 6 months, and 12 months after miscarriage. Main Outcome Measure(s) Scores on GHQ-12 and BDI. Result(s) Half (55%) of the miscarrying women scored high (≥4) on the GHQ-12 immediately, 25% at 3 months; 17.8% at 6 months, and 10.8% at 1 year after miscarriage; 26.8% of the patients scored high on the BDI (≥12) immediately, 18.4% at 3 months, 16.4% at 6 months, and 9.3% at 1 year after miscarriage. Patients who were initially more distressed continued to score higher on both the GHQ-12 and the BDI along the 1-year course when compared with those who were initially less distressed. When compared with the nonpregnant controls, the miscarrying women scored statistically significantly higher on the GHQ-12 and BDI; the differences became not statistically significant only 1 year after miscarriage. Conclusion(s) A statistically significant proportion of patients reported psychological morbidity shortly after miscarriage, but their level of distress reduced over time until they were comparable with the controls 1 year later. Patients who were initially more distressed continued to be throughout the 1-year course.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2008.12.048</identifier><identifier>PMID: 19185858</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abortion, Spontaneous - epidemiology ; Abortion, Spontaneous - psychology ; Adult ; Adult and adolescent clinical studies ; BDI ; Biological and medical sciences ; Depression ; Diseases of mother, fetus and pregnancy ; Female ; Gestational Age ; GHQ-12 ; Gynecology. Andrology. Obstetrics ; Humans ; Internal Medicine ; Longitudinal Studies ; Medical sciences ; Mental Disorders - epidemiology ; Mental Disorders - etiology ; Miscarriage ; Miscellaneous ; Mood disorders ; Morbidity ; Obstetrics and Gynecology ; Parity ; Personality Inventory ; Pregnancy ; Pregnancy. Fetus. Placenta ; Psychiatric Status Rating Scales ; psychological distress ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Social Class ; Stress, Psychological - complications ; Stress, Psychological - epidemiology ; Surveys and Questionnaires ; Time Factors</subject><ispartof>Fertility and sterility, 2010-04, Vol.93 (6), p.1966-1975</ispartof><rights>American Society for Reproductive Medicine</rights><rights>2010 American Society for Reproductive Medicine</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c574t-bdbd5adf2cb7820e508d3b13f01499f1a45ed3d3d35f2902b3494bfcbb330b583</citedby><cites>FETCH-LOGICAL-c574t-bdbd5adf2cb7820e508d3b13f01499f1a45ed3d3d35f2902b3494bfcbb330b583</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fertnstert.2008.12.048$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22637683$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19185858$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lok, Ingrid Hung, M.D</creatorcontrib><creatorcontrib>Yip, Alexander Shing-Kai, M.D</creatorcontrib><creatorcontrib>Lee, Dominic Tak-Sing, M.D</creatorcontrib><creatorcontrib>Sahota, Daljit, Ph.D</creatorcontrib><creatorcontrib>Chung, Tony Kwok-Hung, M.D</creatorcontrib><title>A 1-year longitudinal study of psychological morbidity after miscarriage</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objective To examine the 1-year longitudinal course of psychological outcomes after miscarriage. Design Longitudinal observational study. Setting University-affiliated teaching hospital. Patient(s) 280 miscarrying women and 150 nonpregnant women. Intervention(s) Psychological outcomes were assessed using the 12-item General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) immediately, 3 months, 6 months, and 12 months after miscarriage. Main Outcome Measure(s) Scores on GHQ-12 and BDI. Result(s) Half (55%) of the miscarrying women scored high (≥4) on the GHQ-12 immediately, 25% at 3 months; 17.8% at 6 months, and 10.8% at 1 year after miscarriage; 26.8% of the patients scored high on the BDI (≥12) immediately, 18.4% at 3 months, 16.4% at 6 months, and 9.3% at 1 year after miscarriage. Patients who were initially more distressed continued to score higher on both the GHQ-12 and the BDI along the 1-year course when compared with those who were initially less distressed. When compared with the nonpregnant controls, the miscarrying women scored statistically significantly higher on the GHQ-12 and BDI; the differences became not statistically significant only 1 year after miscarriage. Conclusion(s) A statistically significant proportion of patients reported psychological morbidity shortly after miscarriage, but their level of distress reduced over time until they were comparable with the controls 1 year later. Patients who were initially more distressed continued to be throughout the 1-year course.</description><subject>Abortion, Spontaneous - epidemiology</subject><subject>Abortion, Spontaneous - psychology</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>BDI</subject><subject>Biological and medical sciences</subject><subject>Depression</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Gestational Age</subject><subject>GHQ-12</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Longitudinal Studies</subject><subject>Medical sciences</subject><subject>Mental Disorders - epidemiology</subject><subject>Mental Disorders - etiology</subject><subject>Miscarriage</subject><subject>Miscellaneous</subject><subject>Mood disorders</subject><subject>Morbidity</subject><subject>Obstetrics and Gynecology</subject><subject>Parity</subject><subject>Personality Inventory</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Psychiatric Status Rating Scales</subject><subject>psychological distress</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Social Class</subject><subject>Stress, Psychological - complications</subject><subject>Stress, Psychological - epidemiology</subject><subject>Surveys and Questionnaires</subject><subject>Time Factors</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkctq3DAUhkVpSCbTvELxpnRl9-hmy5tCGtqmEMii7VroOtXUY00lO-C3r8wMCXRVDugcxH8ufD9CFYYGA24_7Bvv0jTmqbwNARANJg0w8QptMOdtzVtOX6MNAOY1EEGu0HXOewBocUcu0RXuseAlNuj-tsL14lSqhjjuwjTbMKqhyqVYquirY17MrzjEXTDl-xCTDjZMS6V82V0dQjYqpaB27g268GrI7uact-jnl88_7u7rh8ev3-5uH2rDOzbV2mrLlfXE6E4QcByEpRpTD5j1vceKcWfpGtyTHoimrGfaG60pBc0F3aL3p7nHFP_MLk9yPcINgxpdnLPsKBUMi5K2SJyUJsWck_PymMJBpUVikCtGuZcvGOWKUWIiC8bS-va8ZNYHZ18az9yK4N1ZoAqBwSc1mpCfdYS0tGvFesOnk84VJE_BJZlNcKNxNiRnJmlj-J9rPv4zxAxhXA357RaX93FOxbMsscylQX5fbV9dBwGsY5TQvyNhq7w</recordid><startdate>20100401</startdate><enddate>20100401</enddate><creator>Lok, Ingrid Hung, M.D</creator><creator>Yip, Alexander Shing-Kai, M.D</creator><creator>Lee, Dominic Tak-Sing, M.D</creator><creator>Sahota, Daljit, Ph.D</creator><creator>Chung, Tony Kwok-Hung, M.D</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100401</creationdate><title>A 1-year longitudinal study of psychological morbidity after miscarriage</title><author>Lok, Ingrid Hung, M.D ; Yip, Alexander Shing-Kai, M.D ; Lee, Dominic Tak-Sing, M.D ; Sahota, Daljit, Ph.D ; Chung, Tony Kwok-Hung, M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c574t-bdbd5adf2cb7820e508d3b13f01499f1a45ed3d3d35f2902b3494bfcbb330b583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Abortion, Spontaneous - epidemiology</topic><topic>Abortion, Spontaneous - psychology</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>BDI</topic><topic>Biological and medical sciences</topic><topic>Depression</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Gestational Age</topic><topic>GHQ-12</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Longitudinal Studies</topic><topic>Medical sciences</topic><topic>Mental Disorders - epidemiology</topic><topic>Mental Disorders - etiology</topic><topic>Miscarriage</topic><topic>Miscellaneous</topic><topic>Mood disorders</topic><topic>Morbidity</topic><topic>Obstetrics and Gynecology</topic><topic>Parity</topic><topic>Personality Inventory</topic><topic>Pregnancy</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Psychiatric Status Rating Scales</topic><topic>psychological distress</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Social Class</topic><topic>Stress, Psychological - complications</topic><topic>Stress, Psychological - epidemiology</topic><topic>Surveys and Questionnaires</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lok, Ingrid Hung, M.D</creatorcontrib><creatorcontrib>Yip, Alexander Shing-Kai, M.D</creatorcontrib><creatorcontrib>Lee, Dominic Tak-Sing, M.D</creatorcontrib><creatorcontrib>Sahota, Daljit, Ph.D</creatorcontrib><creatorcontrib>Chung, Tony Kwok-Hung, M.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lok, Ingrid Hung, M.D</au><au>Yip, Alexander Shing-Kai, M.D</au><au>Lee, Dominic Tak-Sing, M.D</au><au>Sahota, Daljit, Ph.D</au><au>Chung, Tony Kwok-Hung, M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A 1-year longitudinal study of psychological morbidity after miscarriage</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2010-04-01</date><risdate>2010</risdate><volume>93</volume><issue>6</issue><spage>1966</spage><epage>1975</epage><pages>1966-1975</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>Objective To examine the 1-year longitudinal course of psychological outcomes after miscarriage. Design Longitudinal observational study. Setting University-affiliated teaching hospital. Patient(s) 280 miscarrying women and 150 nonpregnant women. Intervention(s) Psychological outcomes were assessed using the 12-item General Health Questionnaire (GHQ-12) and Beck Depression Inventory (BDI) immediately, 3 months, 6 months, and 12 months after miscarriage. Main Outcome Measure(s) Scores on GHQ-12 and BDI. Result(s) Half (55%) of the miscarrying women scored high (≥4) on the GHQ-12 immediately, 25% at 3 months; 17.8% at 6 months, and 10.8% at 1 year after miscarriage; 26.8% of the patients scored high on the BDI (≥12) immediately, 18.4% at 3 months, 16.4% at 6 months, and 9.3% at 1 year after miscarriage. Patients who were initially more distressed continued to score higher on both the GHQ-12 and the BDI along the 1-year course when compared with those who were initially less distressed. When compared with the nonpregnant controls, the miscarrying women scored statistically significantly higher on the GHQ-12 and BDI; the differences became not statistically significant only 1 year after miscarriage. Conclusion(s) A statistically significant proportion of patients reported psychological morbidity shortly after miscarriage, but their level of distress reduced over time until they were comparable with the controls 1 year later. Patients who were initially more distressed continued to be throughout the 1-year course.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>19185858</pmid><doi>10.1016/j.fertnstert.2008.12.048</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Abortion, Spontaneous - epidemiology Abortion, Spontaneous - psychology Adult Adult and adolescent clinical studies BDI Biological and medical sciences Depression Diseases of mother, fetus and pregnancy Female Gestational Age GHQ-12 Gynecology. Andrology. Obstetrics Humans Internal Medicine Longitudinal Studies Medical sciences Mental Disorders - epidemiology Mental Disorders - etiology Miscarriage Miscellaneous Mood disorders Morbidity Obstetrics and Gynecology Parity Personality Inventory Pregnancy Pregnancy. Fetus. Placenta Psychiatric Status Rating Scales psychological distress Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Social Class Stress, Psychological - complications Stress, Psychological - epidemiology Surveys and Questionnaires Time Factors |
| title | A 1-year longitudinal study of psychological morbidity after miscarriage |
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