Efficacy of Ceftriaxone or Meropenem as Initial Therapies in Whipple's Disease

Background & Aims Whipple's disease is a chronic infection caused by the actinomycete Tropheryma whipplei . We conducted a randomized controlled trial of the efficacy of antimicrobials that are able to cross the blood-brain barrier and to which T whipplei is susceptible. Methods Patients fr...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2010-02, Vol.138 (2), p.478-486
Hauptverfasser:	Feurle, Gerhard E, Junga, Natascha S, Marth, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Aged, 80 and over Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Biopsy Ceftriaxone - administration & dosage Ceftriaxone - therapeutic use Drug Therapy, Combination Female Gastroenterology and Hepatology Humans Injections, Intravenous Intestinal Mucosa - microbiology Intestinal Mucosa - pathology Male Middle Aged Remission Induction Thienamycins - administration & dosage Thienamycins - therapeutic use Treatment Outcome Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use Tropheryma Whipple Disease - drug therapy Whipple Disease - pathology
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