Contraceptive responses of mice immunized with purified recombinant mouse zona pellucida subunit 3 (mZP3) proteins

Mouse zona pellucida subunit 3 (mZP3) was tested for efficacy as an immunocontraceptive antigen by comparing the fertility of mice immunized with recombinant mZP3 proteins. Recombinant protein was expressed using either the vaccinia virus T7 mammalian (vmZP3 protein) or baculovirus insect cell (bmZP...

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Veröffentlicht in:	Reproduction (Cambridge, England) England), 2003-07, Vol.126 (1), p.49-59
Hauptverfasser:	Hardy, CM, ten Have, JF, Pekin, J, Beaton, S, Jackson, RJ, Clydesdale, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - blood Baculoviridae - genetics Base Sequence Biological and medical sciences Bioreactors Blotting, Western - methods Contraception, Immunologic Egg Proteins - administration & dosage Egg Proteins - genetics Egg Proteins - immunology Female Freund's Adjuvant Fundamental and applied biological sciences. Psychology Injections, Intraperitoneal Litter Size Membrane Glycoproteins - administration & dosage Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Mice Mice, Inbred BALB C Molecular Sequence Data Receptors, Cell Surface Recombinant Proteins - administration & dosage Recombinant Proteins - immunology Recombinant Proteins - isolation & purification Spodoptera Transduction, Genetic Vaccines, Contraceptive - administration & dosage Vaccines, Contraceptive - immunology Vaccinia virus - genetics Zona Pellucida Glycoproteins
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