Development and validation method for determination of fluoxetine and its main metabolite norfluoxetine by nonaqueous capillary electrophoresis in human urine

A simple, rapid and sensitive procedure using nonaqueous capillary electrophoresis (NACE) to measure fluoxetine and its main metabolite norfluoxetine has been developed and validated. Optimum separation of fluoxetine and norfluoxetine, by measuring at 230 nm, was obtained on a 60 cm × 75 μm capillar...

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Veröffentlicht in:	Talanta (Oxford) 2005-01, Vol.65 (1), p.163-171
Hauptverfasser:	Flores, J. Rodríguez, Nevado, J.J. Berzas, Peñalvo, G. Castañeda, Diez, N. Mora
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Antidepressant and human urine Chemistry Chromatographic methods and physical methods associated with chromatography Exact sciences and technology Fluoxetine Metabolite Nonaqueous capillary electrophoresis Norfluoxetine Other chromatographic methods
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