Application of a classical least-squares regression method to the assay of 1,4-dihydropyridine antihypertensives and their photoproducts

A multicomponent UV spectrophotometric method using a classical least-squares (CLS) algorithm has been developed for the quantitative determination of 1,4-dihydropyridine (DHP) calcium antagonists and respective photoproducts. The procedure was optimized by defining a fractionation scheme for select...

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Veröffentlicht in:	Talanta (Oxford) 2003-02, Vol.59 (2), p.375-382
Hauptverfasser:	Ragno, Gaetano, Vetuschi, Claudio, Risoli, Antonella, Ioele, Giuseppina
Format:	Artikel
Sprache:	eng
Schlagworte:	1,4-Dihydropyridines Analysis Biological and medical sciences Classical least-squares General pharmacology Medical sciences Multivariate spectrophotometry Pharmacology. Drug treatments Photodegradation
Online-Zugang:	Volltext
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