Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for gastroesophageal reflux disease: a prospective, randomized trial
Background A prospective, randomized trial was performed to evaluate the long-term outcome and patient satisfaction of laparoscopic complete 360° fundoplication compared with partial posterior 270° fundoplication. Partial fundoplication is purported to have fewer side effects with a higher failure r...
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| Veröffentlicht in: | Surgical endoscopy 2010-04, Vol.24 (4), p.924-932 |
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| creator | Shaw, John M. Bornman, Philippus C. Callanan, Marie D. Beckingham, Ian J. Metz, David C. |
| description | Background
A prospective, randomized trial was performed to evaluate the long-term outcome and patient satisfaction of laparoscopic complete 360° fundoplication compared with partial posterior 270° fundoplication. Partial fundoplication is purported to have fewer side effects with a higher failure rate in controlling gastroesophageal reflux disease (GERD), while complete fundoplication is thought to result in more dysphagia and gas-related symptoms.
Methods
Patients were randomized to either laparoscopic Nissen (LN) or laparoscopic Toupet (LT) fundoplication. Esophageal manometry, 24-h pH studies, a detailed questionnaire, and a visual analog symptom (VAS) score were completed before and after surgery. A final global outcome questionnaire was performed. Failure was defined as recurrent GERD requiring revision surgery, maintenance proton pump inhibitor (PPI) therapy, or surgery for postoperative dysphagia.
Results
One hundred patients were randomized to LN (50) or LT (50). There were no differences between LN and LT with respect to postoperative symptoms and physiological variables except a higher wrap pressure in the LN group (15.2 vs. 12.0 mmHg). Dysmotility improved in 8/14 (57%) and 6/11 (54%) patients in the LN group and the LT group, respectively, after surgery. There was no correlation between dysmotility and dysphagia both pre- and post surgery in the two groups. Recurrent symptoms of GERD occurred in 8/47 (17.0%) and 8/48 (16.6%) in the LN group and the LT group, respectively. Outcome of patients with dysmotility was similar to those with normal motility in both groups. At final follow-up (59.76 ± 24.23 months), in the LN group, 33/37 (89.1%) would recommend surgery to others, 32/37 (86.4%) would have repeat surgery, and 34/37 (91.8%) felt they were better off than before surgery. The corresponding numbers for the LT group (follow-up = 55.18 ± 25.97 months) were 35/36 (97.2%), 30/36 (83.3%), and 33/36 (91.6%).
Conclusion
LN and LT are equally effective in restoring the lower esophageal sphincter function and provide similar long-term control of GERD with no difference in dysphagia. Esophageal dysmotility had no influence on the outcome of either operation. |
| doi_str_mv | 10.1007/s00464-009-0700-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733816564</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733816564</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-74e9b935287dd86a6ae9a7da69989d8ccdcaca3082868d3b92e8e3978659e4d43</originalsourceid><addsrcrecordid>eNp1kc2KFDEUhYMoTs_oA7iRIMhsLL1J6ieZnQz-QaObcR1uJ7faDFWVMqkS9Tl8YNN046DgKpB89-Scexh7IuClAOheZYC6rSsAU0EHUKl7bCNqJSsphb7PNmAUVLIz9Rk7z_kWCm5E85CdCdNpYyRs2K9tnPbVQmnkcV1cHInHng84Y4rZxTk4_jHkTBPHyf99fxPXmRber5OP8xAcLiFOvI-J7zEvKVKO8xfcEw48UT-s37kPmTDTFUc-F5mZ3BK-0QueinYcw0_yfEkBh0fsQY9Dpsen84J9fvvm5vp9tf307sP1623laoCl6moyO6MaqTvvdYstksHOY2uMNl475x06VKClbrVXOyNJkyrR28ZQ7Wt1wS6PusXN15XyYseQHQ0DThTXbDultGib9kA--4e8jWuaijkrhWmgUaAKJI6QK-FyyWznFEZMP6wAeyjMHguzpTB7KMweZp6ehNfdSP5u4tRQAZ6fAMwOh77syoX8h5Oy1cVgVzh55HJ5mvaU7hz-__ffl_WwxQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>219505303</pqid></control><display><type>article</type><title>Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for gastroesophageal reflux disease: a prospective, randomized trial</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Shaw, John M. ; Bornman, Philippus C. ; Callanan, Marie D. ; Beckingham, Ian J. ; Metz, David C.</creator><creatorcontrib>Shaw, John M. ; Bornman, Philippus C. ; Callanan, Marie D. ; Beckingham, Ian J. ; Metz, David C.</creatorcontrib><description>Background
A prospective, randomized trial was performed to evaluate the long-term outcome and patient satisfaction of laparoscopic complete 360° fundoplication compared with partial posterior 270° fundoplication. Partial fundoplication is purported to have fewer side effects with a higher failure rate in controlling gastroesophageal reflux disease (GERD), while complete fundoplication is thought to result in more dysphagia and gas-related symptoms.
Methods
Patients were randomized to either laparoscopic Nissen (LN) or laparoscopic Toupet (LT) fundoplication. Esophageal manometry, 24-h pH studies, a detailed questionnaire, and a visual analog symptom (VAS) score were completed before and after surgery. A final global outcome questionnaire was performed. Failure was defined as recurrent GERD requiring revision surgery, maintenance proton pump inhibitor (PPI) therapy, or surgery for postoperative dysphagia.
Results
One hundred patients were randomized to LN (50) or LT (50). There were no differences between LN and LT with respect to postoperative symptoms and physiological variables except a higher wrap pressure in the LN group (15.2 vs. 12.0 mmHg). Dysmotility improved in 8/14 (57%) and 6/11 (54%) patients in the LN group and the LT group, respectively, after surgery. There was no correlation between dysmotility and dysphagia both pre- and post surgery in the two groups. Recurrent symptoms of GERD occurred in 8/47 (17.0%) and 8/48 (16.6%) in the LN group and the LT group, respectively. Outcome of patients with dysmotility was similar to those with normal motility in both groups. At final follow-up (59.76 ± 24.23 months), in the LN group, 33/37 (89.1%) would recommend surgery to others, 32/37 (86.4%) would have repeat surgery, and 34/37 (91.8%) felt they were better off than before surgery. The corresponding numbers for the LT group (follow-up = 55.18 ± 25.97 months) were 35/36 (97.2%), 30/36 (83.3%), and 33/36 (91.6%).
Conclusion
LN and LT are equally effective in restoring the lower esophageal sphincter function and provide similar long-term control of GERD with no difference in dysphagia. Esophageal dysmotility had no influence on the outcome of either operation.</description><identifier>ISSN: 0930-2794</identifier><identifier>EISSN: 1432-2218</identifier><identifier>DOI: 10.1007/s00464-009-0700-3</identifier><identifier>PMID: 19789920</identifier><identifier>CODEN: SUREEX</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Abdominal Surgery ; Adult ; Aged ; Biological and medical sciences ; Catheters ; Digestive system. Abdomen ; Dysphagia ; Endoscopy ; Esophageal pH Monitoring ; Esophagus ; Female ; Fundoplication - methods ; Gastroenterology ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroesophageal reflux ; Gastroesophageal Reflux - surgery ; Gynecology ; Hepatology ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Laparoscopy ; Laparoscopy - methods ; Male ; Manometry ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Miscellaneous ; Motility ; Observatories ; Other diseases. Semiology ; Patient Satisfaction ; Proctology ; Prospective Studies ; Questionnaires ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Recurrence ; Statistics, Nonparametric ; Surgery ; Surveys and Questionnaires ; Treatment Outcome</subject><ispartof>Surgical endoscopy, 2010-04, Vol.24 (4), p.924-932</ispartof><rights>Springer Science+Business Media, LLC 2009</rights><rights>2015 INIST-CNRS</rights><rights>Springer Science+Business Media, LLC 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-74e9b935287dd86a6ae9a7da69989d8ccdcaca3082868d3b92e8e3978659e4d43</citedby><cites>FETCH-LOGICAL-c400t-74e9b935287dd86a6ae9a7da69989d8ccdcaca3082868d3b92e8e3978659e4d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00464-009-0700-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00464-009-0700-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22685647$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19789920$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shaw, John M.</creatorcontrib><creatorcontrib>Bornman, Philippus C.</creatorcontrib><creatorcontrib>Callanan, Marie D.</creatorcontrib><creatorcontrib>Beckingham, Ian J.</creatorcontrib><creatorcontrib>Metz, David C.</creatorcontrib><title>Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for gastroesophageal reflux disease: a prospective, randomized trial</title><title>Surgical endoscopy</title><addtitle>Surg Endosc</addtitle><addtitle>Surg Endosc</addtitle><description>Background
A prospective, randomized trial was performed to evaluate the long-term outcome and patient satisfaction of laparoscopic complete 360° fundoplication compared with partial posterior 270° fundoplication. Partial fundoplication is purported to have fewer side effects with a higher failure rate in controlling gastroesophageal reflux disease (GERD), while complete fundoplication is thought to result in more dysphagia and gas-related symptoms.
Methods
Patients were randomized to either laparoscopic Nissen (LN) or laparoscopic Toupet (LT) fundoplication. Esophageal manometry, 24-h pH studies, a detailed questionnaire, and a visual analog symptom (VAS) score were completed before and after surgery. A final global outcome questionnaire was performed. Failure was defined as recurrent GERD requiring revision surgery, maintenance proton pump inhibitor (PPI) therapy, or surgery for postoperative dysphagia.
Results
One hundred patients were randomized to LN (50) or LT (50). There were no differences between LN and LT with respect to postoperative symptoms and physiological variables except a higher wrap pressure in the LN group (15.2 vs. 12.0 mmHg). Dysmotility improved in 8/14 (57%) and 6/11 (54%) patients in the LN group and the LT group, respectively, after surgery. There was no correlation between dysmotility and dysphagia both pre- and post surgery in the two groups. Recurrent symptoms of GERD occurred in 8/47 (17.0%) and 8/48 (16.6%) in the LN group and the LT group, respectively. Outcome of patients with dysmotility was similar to those with normal motility in both groups. At final follow-up (59.76 ± 24.23 months), in the LN group, 33/37 (89.1%) would recommend surgery to others, 32/37 (86.4%) would have repeat surgery, and 34/37 (91.8%) felt they were better off than before surgery. The corresponding numbers for the LT group (follow-up = 55.18 ± 25.97 months) were 35/36 (97.2%), 30/36 (83.3%), and 33/36 (91.6%).
Conclusion
LN and LT are equally effective in restoring the lower esophageal sphincter function and provide similar long-term control of GERD with no difference in dysphagia. Esophageal dysmotility had no influence on the outcome of either operation.</description><subject>Abdominal Surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Catheters</subject><subject>Digestive system. Abdomen</subject><subject>Dysphagia</subject><subject>Endoscopy</subject><subject>Esophageal pH Monitoring</subject><subject>Esophagus</subject><subject>Female</subject><subject>Fundoplication - methods</subject><subject>Gastroenterology</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastroesophageal reflux</subject><subject>Gastroesophageal Reflux - surgery</subject><subject>Gynecology</subject><subject>Hepatology</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Laparoscopy</subject><subject>Laparoscopy - methods</subject><subject>Male</subject><subject>Manometry</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Motility</subject><subject>Observatories</subject><subject>Other diseases. Semiology</subject><subject>Patient Satisfaction</subject><subject>Proctology</subject><subject>Prospective Studies</subject><subject>Questionnaires</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Recurrence</subject><subject>Statistics, Nonparametric</subject><subject>Surgery</subject><subject>Surveys and Questionnaires</subject><subject>Treatment Outcome</subject><issn>0930-2794</issn><issn>1432-2218</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc2KFDEUhYMoTs_oA7iRIMhsLL1J6ieZnQz-QaObcR1uJ7faDFWVMqkS9Tl8YNN046DgKpB89-Scexh7IuClAOheZYC6rSsAU0EHUKl7bCNqJSsphb7PNmAUVLIz9Rk7z_kWCm5E85CdCdNpYyRs2K9tnPbVQmnkcV1cHInHng84Y4rZxTk4_jHkTBPHyf99fxPXmRber5OP8xAcLiFOvI-J7zEvKVKO8xfcEw48UT-s37kPmTDTFUc-F5mZ3BK-0QueinYcw0_yfEkBh0fsQY9Dpsen84J9fvvm5vp9tf307sP1623laoCl6moyO6MaqTvvdYstksHOY2uMNl475x06VKClbrVXOyNJkyrR28ZQ7Wt1wS6PusXN15XyYseQHQ0DThTXbDultGib9kA--4e8jWuaijkrhWmgUaAKJI6QK-FyyWznFEZMP6wAeyjMHguzpTB7KMweZp6ehNfdSP5u4tRQAZ6fAMwOh77syoX8h5Oy1cVgVzh55HJ5mvaU7hz-__ffl_WwxQ</recordid><startdate>20100401</startdate><enddate>20100401</enddate><creator>Shaw, John M.</creator><creator>Bornman, Philippus C.</creator><creator>Callanan, Marie D.</creator><creator>Beckingham, Ian J.</creator><creator>Metz, David C.</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20100401</creationdate><title>Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for gastroesophageal reflux disease: a prospective, randomized trial</title><author>Shaw, John M. ; Bornman, Philippus C. ; Callanan, Marie D. ; Beckingham, Ian J. ; Metz, David C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-74e9b935287dd86a6ae9a7da69989d8ccdcaca3082868d3b92e8e3978659e4d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Abdominal Surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Catheters</topic><topic>Digestive system. Abdomen</topic><topic>Dysphagia</topic><topic>Endoscopy</topic><topic>Esophageal pH Monitoring</topic><topic>Esophagus</topic><topic>Female</topic><topic>Fundoplication - methods</topic><topic>Gastroenterology</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastroesophageal reflux</topic><topic>Gastroesophageal Reflux - surgery</topic><topic>Gynecology</topic><topic>Hepatology</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Laparoscopy</topic><topic>Laparoscopy - methods</topic><topic>Male</topic><topic>Manometry</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Motility</topic><topic>Observatories</topic><topic>Other diseases. Semiology</topic><topic>Patient Satisfaction</topic><topic>Proctology</topic><topic>Prospective Studies</topic><topic>Questionnaires</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Recurrence</topic><topic>Statistics, Nonparametric</topic><topic>Surgery</topic><topic>Surveys and Questionnaires</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shaw, John M.</creatorcontrib><creatorcontrib>Bornman, Philippus C.</creatorcontrib><creatorcontrib>Callanan, Marie D.</creatorcontrib><creatorcontrib>Beckingham, Ian J.</creatorcontrib><creatorcontrib>Metz, David C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Surgical endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shaw, John M.</au><au>Bornman, Philippus C.</au><au>Callanan, Marie D.</au><au>Beckingham, Ian J.</au><au>Metz, David C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for gastroesophageal reflux disease: a prospective, randomized trial</atitle><jtitle>Surgical endoscopy</jtitle><stitle>Surg Endosc</stitle><addtitle>Surg Endosc</addtitle><date>2010-04-01</date><risdate>2010</risdate><volume>24</volume><issue>4</issue><spage>924</spage><epage>932</epage><pages>924-932</pages><issn>0930-2794</issn><eissn>1432-2218</eissn><coden>SUREEX</coden><abstract>Background
A prospective, randomized trial was performed to evaluate the long-term outcome and patient satisfaction of laparoscopic complete 360° fundoplication compared with partial posterior 270° fundoplication. Partial fundoplication is purported to have fewer side effects with a higher failure rate in controlling gastroesophageal reflux disease (GERD), while complete fundoplication is thought to result in more dysphagia and gas-related symptoms.
Methods
Patients were randomized to either laparoscopic Nissen (LN) or laparoscopic Toupet (LT) fundoplication. Esophageal manometry, 24-h pH studies, a detailed questionnaire, and a visual analog symptom (VAS) score were completed before and after surgery. A final global outcome questionnaire was performed. Failure was defined as recurrent GERD requiring revision surgery, maintenance proton pump inhibitor (PPI) therapy, or surgery for postoperative dysphagia.
Results
One hundred patients were randomized to LN (50) or LT (50). There were no differences between LN and LT with respect to postoperative symptoms and physiological variables except a higher wrap pressure in the LN group (15.2 vs. 12.0 mmHg). Dysmotility improved in 8/14 (57%) and 6/11 (54%) patients in the LN group and the LT group, respectively, after surgery. There was no correlation between dysmotility and dysphagia both pre- and post surgery in the two groups. Recurrent symptoms of GERD occurred in 8/47 (17.0%) and 8/48 (16.6%) in the LN group and the LT group, respectively. Outcome of patients with dysmotility was similar to those with normal motility in both groups. At final follow-up (59.76 ± 24.23 months), in the LN group, 33/37 (89.1%) would recommend surgery to others, 32/37 (86.4%) would have repeat surgery, and 34/37 (91.8%) felt they were better off than before surgery. The corresponding numbers for the LT group (follow-up = 55.18 ± 25.97 months) were 35/36 (97.2%), 30/36 (83.3%), and 33/36 (91.6%).
Conclusion
LN and LT are equally effective in restoring the lower esophageal sphincter function and provide similar long-term control of GERD with no difference in dysphagia. Esophageal dysmotility had no influence on the outcome of either operation.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>19789920</pmid><doi>10.1007/s00464-009-0700-3</doi><tpages>9</tpages></addata></record> |
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| ispartof | Surgical endoscopy, 2010-04, Vol.24 (4), p.924-932 |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Abdominal Surgery Adult Aged Biological and medical sciences Catheters Digestive system. Abdomen Dysphagia Endoscopy Esophageal pH Monitoring Esophagus Female Fundoplication - methods Gastroenterology Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal reflux Gastroesophageal Reflux - surgery Gynecology Hepatology Humans Investigative techniques, diagnostic techniques (general aspects) Laparoscopy Laparoscopy - methods Male Manometry Medical sciences Medicine Medicine & Public Health Middle Aged Miscellaneous Motility Observatories Other diseases. Semiology Patient Satisfaction Proctology Prospective Studies Questionnaires Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Recurrence Statistics, Nonparametric Surgery Surveys and Questionnaires Treatment Outcome |
| title | Long-term outcome of laparoscopic Nissen and laparoscopic Toupet fundoplication for gastroesophageal reflux disease: a prospective, randomized trial |
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