Sex-Related Differences in the Risk Factor Profile and Medications of Patients With Atrial Fibrillation Recruited in J-TRACE
Background: Clinical characteristics, including risk factors for thromboembolism, and medications differ between men and women with atrial fibrillation (AF) in Western countries. Whether such a difference exists for Japanese patients with AF is unclear, so data from J-TRACE were used to investigate...
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| Veröffentlicht in: | Circulation Journal 2010, Vol.74(4), pp.650-654 |
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| creator | Inoue, Hiroshi Nozawa, Takashi Hirai, Tadakazu Goto, Shinya Origasa, Hideki Shimada, Kazuyuki Uchiyama, Shinichiro Hirabayashi, Takayuki Koretsune, Yukihiro Ono, Shiro Hasegawa, Tooru Sasagawa, Yasuo Kaneko, Yoshiaki Ikeda, Yasuo Investigators, J-TRACE |
| description | Background: Clinical characteristics, including risk factors for thromboembolism, and medications differ between men and women with atrial fibrillation (AF) in Western countries. Whether such a difference exists for Japanese patients with AF is unclear, so data from J-TRACE were used to investigate this issue. Methods and Results: A total of 2,892 patients (2,028 men, 864 women; 70.3 years old) with AF were analyzed for the respective prevalences of risk factors and medications. CHADS2 score was calculated to determine thromboembolic risk level. Women were older (P |
| doi_str_mv | 10.1253/circj.CJ-09-0802 |
| format | Article |
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Whether such a difference exists for Japanese patients with AF is unclear, so data from J-TRACE were used to investigate this issue. Methods and Results: A total of 2,892 patients (2,028 men, 864 women; 70.3 years old) with AF were analyzed for the respective prevalences of risk factors and medications. CHADS2 score was calculated to determine thromboembolic risk level. Women were older (P<0.001), and more frequently had heart failure (P<0.001), and hypertension (P=0.051) than men. The proportion of subjects aged 75 years or older was higher among women than among men (P<0.001). CHADS2 score was therefore significantly higher in women than in men (2.05±1.29 vs 1.88±1.33, P<0.001). Sex-related differences were not observed for the prevalence of diabetes mellitus, myocardial infarction or ischemic stroke, nor did warfarin usage differ between men and women. Conclusions: Sex-related differences were observed in the risk factor profile and medications of Japanese patients with AF. CHADS2 score was higher in women than in men. (Circ J 2010; 74: 650-654)</description><identifier>ISSN: 1346-9843</identifier><identifier>EISSN: 1347-4820</identifier><identifier>DOI: 10.1253/circj.CJ-09-0802</identifier><identifier>PMID: 20173301</identifier><language>eng</language><publisher>Japan: The Japanese Circulation Society</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aspirin ; Atrial fibrillation ; Atrial Fibrillation - complications ; CHADS2 score ; Clinical characteristics ; Female ; Humans ; Hypoglycemic Agents ; Japan ; Male ; Medications ; Middle Aged ; Platelet Aggregation Inhibitors ; Prescription Drugs ; Registries ; Risk Factors ; Sex Characteristics ; Sex differences ; Thromboembolism - epidemiology ; Thromboembolism - prevention & control ; Warfarin</subject><ispartof>Circulation Journal, 2010, Vol.74(4), pp.650-654</ispartof><rights>2010 THE JAPANESE CIRCULATION SOCIETY</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c493t-24b91672be50f4eef3d59aee85ec11707675682f800521d76e71051c720842443</citedby><cites>FETCH-LOGICAL-c493t-24b91672be50f4eef3d59aee85ec11707675682f800521d76e71051c720842443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20173301$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Inoue, Hiroshi</creatorcontrib><creatorcontrib>Nozawa, Takashi</creatorcontrib><creatorcontrib>Hirai, Tadakazu</creatorcontrib><creatorcontrib>Goto, Shinya</creatorcontrib><creatorcontrib>Origasa, Hideki</creatorcontrib><creatorcontrib>Shimada, Kazuyuki</creatorcontrib><creatorcontrib>Uchiyama, Shinichiro</creatorcontrib><creatorcontrib>Hirabayashi, Takayuki</creatorcontrib><creatorcontrib>Koretsune, Yukihiro</creatorcontrib><creatorcontrib>Ono, Shiro</creatorcontrib><creatorcontrib>Hasegawa, Tooru</creatorcontrib><creatorcontrib>Sasagawa, Yasuo</creatorcontrib><creatorcontrib>Kaneko, Yoshiaki</creatorcontrib><creatorcontrib>Ikeda, Yasuo</creatorcontrib><creatorcontrib>Investigators, J-TRACE</creatorcontrib><creatorcontrib>J-TRACE Investigators</creatorcontrib><title>Sex-Related Differences in the Risk Factor Profile and Medications of Patients With Atrial Fibrillation Recruited in J-TRACE</title><title>Circulation Journal</title><addtitle>Circ J</addtitle><description>Background: Clinical characteristics, including risk factors for thromboembolism, and medications differ between men and women with atrial fibrillation (AF) in Western countries. Whether such a difference exists for Japanese patients with AF is unclear, so data from J-TRACE were used to investigate this issue. Methods and Results: A total of 2,892 patients (2,028 men, 864 women; 70.3 years old) with AF were analyzed for the respective prevalences of risk factors and medications. CHADS2 score was calculated to determine thromboembolic risk level. Women were older (P<0.001), and more frequently had heart failure (P<0.001), and hypertension (P=0.051) than men. The proportion of subjects aged 75 years or older was higher among women than among men (P<0.001). CHADS2 score was therefore significantly higher in women than in men (2.05±1.29 vs 1.88±1.33, P<0.001). Sex-related differences were not observed for the prevalence of diabetes mellitus, myocardial infarction or ischemic stroke, nor did warfarin usage differ between men and women. Conclusions: Sex-related differences were observed in the risk factor profile and medications of Japanese patients with AF. CHADS2 score was higher in women than in men. (Circ J 2010; 74: 650-654)</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aspirin</subject><subject>Atrial fibrillation</subject><subject>Atrial Fibrillation - complications</subject><subject>CHADS2 score</subject><subject>Clinical characteristics</subject><subject>Female</subject><subject>Humans</subject><subject>Hypoglycemic Agents</subject><subject>Japan</subject><subject>Male</subject><subject>Medications</subject><subject>Middle Aged</subject><subject>Platelet Aggregation Inhibitors</subject><subject>Prescription Drugs</subject><subject>Registries</subject><subject>Risk Factors</subject><subject>Sex Characteristics</subject><subject>Sex differences</subject><subject>Thromboembolism - epidemiology</subject><subject>Thromboembolism - prevention & control</subject><subject>Warfarin</subject><issn>1346-9843</issn><issn>1347-4820</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM9v0zAUgC3ExMbgzgn5xsnj-Ufi5FiFlVFt2lSGOFqu80xd0mTYrgTS_niSttsu9jt877P1EfKBwwUXhfzsQnSbi2bBoGZQgXhFzrhUmqlKwOv9XLK6UvKUvE1pAyBqKOo35FQA11ICPyOP3_EvW2JnM7b0S_AeI_YOEw09zWuky5B-07l1eYj0Lg4-dEht39IbbIOzOQx9ooOnd-OIfU70Z8hrOssx2I7OwyqGrttTdIku7sL0ymhesPvlrLl8R0687RK-P97n5Mf88r65Yte3X781s2vmVC0zE2pV81KLFRbgFaKXbVFbxKpAx7kGXeqirISvAArBW12i5lBwpwVUSiglz8mng_chDn92mLLZhuRw_FqPwy6ZsUU1teIjCQfSxSGliN48xLC18Z_hYKbkZp_cNAsDtZmSjysfj_Ldaovt88JT4xGYH4BNyvYXPgM25uA6PBq1Mmo6XswvwNpGg738D9q5lcM</recordid><startdate>2010</startdate><enddate>2010</enddate><creator>Inoue, Hiroshi</creator><creator>Nozawa, Takashi</creator><creator>Hirai, Tadakazu</creator><creator>Goto, Shinya</creator><creator>Origasa, Hideki</creator><creator>Shimada, Kazuyuki</creator><creator>Uchiyama, Shinichiro</creator><creator>Hirabayashi, Takayuki</creator><creator>Koretsune, Yukihiro</creator><creator>Ono, Shiro</creator><creator>Hasegawa, Tooru</creator><creator>Sasagawa, Yasuo</creator><creator>Kaneko, Yoshiaki</creator><creator>Ikeda, Yasuo</creator><creator>Investigators, J-TRACE</creator><general>The Japanese Circulation Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2010</creationdate><title>Sex-Related Differences in the Risk Factor Profile and Medications of Patients With Atrial Fibrillation Recruited in J-TRACE</title><author>Inoue, Hiroshi ; Nozawa, Takashi ; Hirai, Tadakazu ; Goto, Shinya ; Origasa, Hideki ; Shimada, Kazuyuki ; Uchiyama, Shinichiro ; Hirabayashi, Takayuki ; Koretsune, Yukihiro ; Ono, Shiro ; Hasegawa, Tooru ; Sasagawa, Yasuo ; Kaneko, Yoshiaki ; Ikeda, Yasuo ; Investigators, J-TRACE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-24b91672be50f4eef3d59aee85ec11707675682f800521d76e71051c720842443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aspirin</topic><topic>Atrial fibrillation</topic><topic>Atrial Fibrillation - complications</topic><topic>CHADS2 score</topic><topic>Clinical characteristics</topic><topic>Female</topic><topic>Humans</topic><topic>Hypoglycemic Agents</topic><topic>Japan</topic><topic>Male</topic><topic>Medications</topic><topic>Middle Aged</topic><topic>Platelet Aggregation Inhibitors</topic><topic>Prescription Drugs</topic><topic>Registries</topic><topic>Risk Factors</topic><topic>Sex Characteristics</topic><topic>Sex differences</topic><topic>Thromboembolism - epidemiology</topic><topic>Thromboembolism - prevention & control</topic><topic>Warfarin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inoue, Hiroshi</creatorcontrib><creatorcontrib>Nozawa, Takashi</creatorcontrib><creatorcontrib>Hirai, Tadakazu</creatorcontrib><creatorcontrib>Goto, Shinya</creatorcontrib><creatorcontrib>Origasa, Hideki</creatorcontrib><creatorcontrib>Shimada, Kazuyuki</creatorcontrib><creatorcontrib>Uchiyama, Shinichiro</creatorcontrib><creatorcontrib>Hirabayashi, Takayuki</creatorcontrib><creatorcontrib>Koretsune, Yukihiro</creatorcontrib><creatorcontrib>Ono, Shiro</creatorcontrib><creatorcontrib>Hasegawa, Tooru</creatorcontrib><creatorcontrib>Sasagawa, Yasuo</creatorcontrib><creatorcontrib>Kaneko, Yoshiaki</creatorcontrib><creatorcontrib>Ikeda, Yasuo</creatorcontrib><creatorcontrib>Investigators, J-TRACE</creatorcontrib><creatorcontrib>J-TRACE Investigators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inoue, Hiroshi</au><au>Nozawa, Takashi</au><au>Hirai, Tadakazu</au><au>Goto, Shinya</au><au>Origasa, Hideki</au><au>Shimada, Kazuyuki</au><au>Uchiyama, Shinichiro</au><au>Hirabayashi, Takayuki</au><au>Koretsune, Yukihiro</au><au>Ono, Shiro</au><au>Hasegawa, Tooru</au><au>Sasagawa, Yasuo</au><au>Kaneko, Yoshiaki</au><au>Ikeda, Yasuo</au><au>Investigators, J-TRACE</au><aucorp>J-TRACE Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sex-Related Differences in the Risk Factor Profile and Medications of Patients With Atrial Fibrillation Recruited in J-TRACE</atitle><jtitle>Circulation Journal</jtitle><addtitle>Circ J</addtitle><date>2010</date><risdate>2010</risdate><volume>74</volume><issue>4</issue><spage>650</spage><epage>654</epage><pages>650-654</pages><issn>1346-9843</issn><eissn>1347-4820</eissn><abstract>Background: Clinical characteristics, including risk factors for thromboembolism, and medications differ between men and women with atrial fibrillation (AF) in Western countries. Whether such a difference exists for Japanese patients with AF is unclear, so data from J-TRACE were used to investigate this issue. Methods and Results: A total of 2,892 patients (2,028 men, 864 women; 70.3 years old) with AF were analyzed for the respective prevalences of risk factors and medications. CHADS2 score was calculated to determine thromboembolic risk level. Women were older (P<0.001), and more frequently had heart failure (P<0.001), and hypertension (P=0.051) than men. The proportion of subjects aged 75 years or older was higher among women than among men (P<0.001). CHADS2 score was therefore significantly higher in women than in men (2.05±1.29 vs 1.88±1.33, P<0.001). Sex-related differences were not observed for the prevalence of diabetes mellitus, myocardial infarction or ischemic stroke, nor did warfarin usage differ between men and women. Conclusions: Sex-related differences were observed in the risk factor profile and medications of Japanese patients with AF. CHADS2 score was higher in women than in men. (Circ J 2010; 74: 650-654)</abstract><cop>Japan</cop><pub>The Japanese Circulation Society</pub><pmid>20173301</pmid><doi>10.1253/circj.CJ-09-0802</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Aspirin Atrial fibrillation Atrial Fibrillation - complications CHADS2 score Clinical characteristics Female Humans Hypoglycemic Agents Japan Male Medications Middle Aged Platelet Aggregation Inhibitors Prescription Drugs Registries Risk Factors Sex Characteristics Sex differences Thromboembolism - epidemiology Thromboembolism - prevention & control Warfarin |
| title | Sex-Related Differences in the Risk Factor Profile and Medications of Patients With Atrial Fibrillation Recruited in J-TRACE |
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