Feasibility and efficacy of chronic transfusion for stroke prevention in children with sickle cell disease

Objectives: In children with sickle cell disease (SCD), chronic transfusion to maintain haemoglobin S (HbS) below 30% markedly decreases both the risk of a first stroke when transcranial Doppler (TCD) ultrasonography shows abnormal cerebral blood flow velocities and the risk of recurrent stroke. Ma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of haematology 2010-03, Vol.84 (3), p.259-265
Hauptverfasser:	Mirre, Elsa, Brousse, Valentine, Berteloot, Laureline, Lambot-Juhan, Karen, Verlhac, Suzanne, Boulat, Claire, Dumont, Marie-Dominique, Lenoir, Gérard, De Montalembert, Mariane
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anemia, Sickle Cell - complications Anemia, Sickle Cell - therapy Blood Transfusion Cerebrovascular Circulation Chelation Therapy Child Child, Preschool Erythrocytes - immunology Feasibility Studies Female Follow-Up Studies Hemoglobin, Sickle - analysis Humans Iron Chelating Agents - therapeutic use Iron Overload - drug therapy Iron Overload - etiology Isoantibodies - biosynthesis Magnetic Resonance Imaging Male Paris Retrospective Studies Secondary Prevention sickle cell disease stroke Stroke - diagnostic imaging Stroke - etiology Stroke - prevention & control transcranial Doppler transfusion Ultrasonography, Doppler, Transcranial
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!