Synthetic Applications of Pd(II)-Catalyzed C−H Carboxylation and Mechanistic Insights: Expedient Routes to Anthranilic Acids, Oxazolinones, and Quinazolinones

A Pd(II)-catalyzed reaction protocol for the carboxylation of ortho-C−H bonds in anilides to form N-acyl anthranilic acids has been developed. This reaction procedure provides a novel and efficient strategy for the rapid assembly of biologically and pharmaceutically significant molecules, such as be...

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Veröffentlicht in:Journal of the American Chemical Society 2010-01, Vol.132 (2), p.686-693
Hauptverfasser: Giri, Ramesh, Lam, Jonathan K, Yu, Jin-Quan
Format: Artikel
Sprache:eng
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