Leptin and ghrelin in Korean systemic lupus erythematosus
Elevated serum leptin levels have been described in patients with systemic lupus erythematosus (SLE), however these studies have provided no information regarding the ghrelin levels. We investigated the clinical significance of serum leptin and ghrelin levels in SLE. The leptin levels of SLE patient...
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| Veröffentlicht in: | Lupus 2010-02, Vol.19 (2), p.170-174 |
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| creator | Kim, H-A. Choi, G-S. Jeon, J-Y. Yoon, J-M. Sung, J-M. Suh, C-H. |
| description | Elevated serum leptin levels have been described in patients with systemic lupus erythematosus (SLE), however these studies have provided no information regarding the ghrelin levels. We investigated the clinical significance of serum leptin and ghrelin levels in SLE. The leptin levels of SLE patients were higher than those of normal healthy controls, while the ghrelin levels of the SLE were lower. In addition, the ghrelin levels were significantly lower in SLE patients with arthritis and hematologic disorder. Taken together, these findings suggest that leptin and ghrelin play a role in clinical manifestations observed in SLE. Lupus (2010) 19, 170—174. |
| doi_str_mv | 10.1177/0961203309350321 |
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We investigated the clinical significance of serum leptin and ghrelin levels in SLE. The leptin levels of SLE patients were higher than those of normal healthy controls, while the ghrelin levels of the SLE were lower. In addition, the ghrelin levels were significantly lower in SLE patients with arthritis and hematologic disorder. Taken together, these findings suggest that leptin and ghrelin play a role in clinical manifestations observed in SLE. 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Lupus (2010) 19, 170—174.</description><subject>Adult</subject><subject>Alopecia</subject><subject>Arthritis</subject><subject>Arthritis - blood</subject><subject>Arthritis - complications</subject><subject>Asian Continental Ancestry Group</subject><subject>Atherosclerosis</subject><subject>Baldness</subject><subject>Body fat</subject><subject>Body mass index</subject><subject>Case-Control Studies</subject><subject>Cytokines</subject><subject>Drug dosages</subject><subject>Female</subject><subject>Ghrelin - blood</subject><subject>Hematologic Diseases - blood</subject><subject>Hematologic Diseases - complications</subject><subject>Humans</subject><subject>Insulin resistance</subject><subject>Kidney diseases</subject><subject>Korea</subject><subject>Leptin - blood</subject><subject>Lupus</subject><subject>Lupus Erythematosus, Systemic - blood</subject><subject>Male</subject><subject>Mortality</subject><subject>Patients</subject><subject>Prospective Studies</subject><subject>Regression analysis</subject><subject>Rheumatology</subject><subject>Ulcers</subject><subject>Young Adult</subject><issn>0961-2033</issn><issn>1477-0962</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kMtLAzEQxoMotlbvnmTxoKfVJJNHc5TiCwte9Lyk2dl2y75Mdg_9701poVBQCEzI95tvMh8h14w-MKb1IzWKcQpADUgKnJ2QMRNap_Gdn5LxVk63-ohchLCmlAIz6pyMmDFKGqHGxMyx68smsU2eLFceq3iP56P1aJskbEKPdemSauiGkKDf9Cusbd-GIVySs8JWAa_2dUK-X56_Zm_p_PP1ffY0Tx0Y0acC6ZQ55FrSRZ6DQ8gpt1BIheCE00qA5ZwDU7m0KHkhuZLKLkwx5SZXFibkfufb-fZnwNBndRkcVpVtsB1CpgGmVAshInn3L8kZ11PGTARvj8B1O_gmbpHFr6jopXmE6A5yvg3BY5F1vqyt32SMZtv0s-P0Y8vN3ndY1JgfGvZxRyDdAcEu8TD0T8Nf77WKQA</recordid><startdate>201002</startdate><enddate>201002</enddate><creator>Kim, H-A.</creator><creator>Choi, G-S.</creator><creator>Jeon, J-Y.</creator><creator>Yoon, J-M.</creator><creator>Sung, J-M.</creator><creator>Suh, C-H.</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>201002</creationdate><title>Leptin and ghrelin in Korean systemic lupus erythematosus</title><author>Kim, H-A. ; Choi, G-S. ; Jeon, J-Y. ; Yoon, J-M. ; Sung, J-M. ; Suh, C-H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c394t-4e081ce2750bdd3ce3d02a3f56e3c4c7643a222316d5ae52f52656ab9f829d6a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Alopecia</topic><topic>Arthritis</topic><topic>Arthritis - blood</topic><topic>Arthritis - complications</topic><topic>Asian Continental Ancestry Group</topic><topic>Atherosclerosis</topic><topic>Baldness</topic><topic>Body fat</topic><topic>Body mass index</topic><topic>Case-Control Studies</topic><topic>Cytokines</topic><topic>Drug dosages</topic><topic>Female</topic><topic>Ghrelin - blood</topic><topic>Hematologic Diseases - blood</topic><topic>Hematologic Diseases - complications</topic><topic>Humans</topic><topic>Insulin resistance</topic><topic>Kidney diseases</topic><topic>Korea</topic><topic>Leptin - blood</topic><topic>Lupus</topic><topic>Lupus Erythematosus, Systemic - blood</topic><topic>Male</topic><topic>Mortality</topic><topic>Patients</topic><topic>Prospective Studies</topic><topic>Regression analysis</topic><topic>Rheumatology</topic><topic>Ulcers</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, H-A.</creatorcontrib><creatorcontrib>Choi, G-S.</creatorcontrib><creatorcontrib>Jeon, J-Y.</creatorcontrib><creatorcontrib>Yoon, J-M.</creatorcontrib><creatorcontrib>Sung, J-M.</creatorcontrib><creatorcontrib>Suh, C-H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Lupus</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, H-A.</au><au>Choi, G-S.</au><au>Jeon, J-Y.</au><au>Yoon, J-M.</au><au>Sung, J-M.</au><au>Suh, C-H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Leptin and ghrelin in Korean systemic lupus erythematosus</atitle><jtitle>Lupus</jtitle><addtitle>Lupus</addtitle><date>2010-02</date><risdate>2010</risdate><volume>19</volume><issue>2</issue><spage>170</spage><epage>174</epage><pages>170-174</pages><issn>0961-2033</issn><eissn>1477-0962</eissn><abstract>Elevated serum leptin levels have been described in patients with systemic lupus erythematosus (SLE), however these studies have provided no information regarding the ghrelin levels. 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| subjects | Adult Alopecia Arthritis Arthritis - blood Arthritis - complications Asian Continental Ancestry Group Atherosclerosis Baldness Body fat Body mass index Case-Control Studies Cytokines Drug dosages Female Ghrelin - blood Hematologic Diseases - blood Hematologic Diseases - complications Humans Insulin resistance Kidney diseases Korea Leptin - blood Lupus Lupus Erythematosus, Systemic - blood Male Mortality Patients Prospective Studies Regression analysis Rheumatology Ulcers Young Adult |
| title | Leptin and ghrelin in Korean systemic lupus erythematosus |
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