Nitric oxide mediates membrane depolarization-promoted survival of rat neuronal PC12 cells

Membrane depolarization promotes neuronal survival through increases in intracellular calcium. Nitric oxide (NO) is a signaling molecule involved in many neuronal activity-dependent events. Since neuronal NO is generated by NO synthase (NOS) in a calcium-dependent manner and was shown to promote cel...

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Veröffentlicht in:	Neuroscience letters 2003-07, Vol.344 (3), p.209-211
Hauptverfasser:	Kim, Tae Woon, Lee, Chang-Han, Choi, Chang-Young, Kwon, Nyoun Soo, Baek, Kwang Jin, Kim, Yang-Gyun, Yun, Hye-Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Differentiation Cell Membrane - physiology Cell Survival cGMP Cyclic GMP - metabolism Fundamental and applied biological sciences. Psychology Isolated neuron and nerve. Neuroglia Membrane depolarization Mitogen-Activated Protein Kinases - antagonists & inhibitors Neurons - cytology Neurons - drug effects Nitric oxide Nitric Oxide - metabolism Nitric Oxide Donors - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Organophosphonates - pharmacology PC12 Cells Pheochromocytoma-12 cells Potassium - metabolism Potassium - pharmacology Potassium chloride Ras ras Proteins - genetics ras Proteins - metabolism Rats Survival Transfection Vertebrates: nervous system and sense organs
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