Synthesis, refolding and protective immune responses of a potential antigen for human Respiratory Syncytial Virus vaccine

The design of new antigens with both high immunogenic and safety properties is of particular interest to vaccine against infectious diseases. In the present study, we describe the synthesis and the refolding of peptide G20 derived from the Human Respiratory Syncytial Virus (hRSV) G-protein. G20 (MEF...

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Veröffentlicht in:	The journal of peptide research 2003-07, Vol.62 (1), p.27-36
Hauptverfasser:	Klinguer-Hamour, C., Bussat, M.-C., Plotnicky, H., Velin, D., Corvaïa, N., Nguyen, T., Beck, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Viral - biosynthesis Antibodies, Viral - blood Antigens, Viral - chemistry Antigens, Viral - immunology Circular Dichroism Cysteine - chemistry disulfide bridges Epitopes, B-Lymphocyte - chemistry Epitopes, B-Lymphocyte - immunology Epitopes, T-Lymphocyte - chemistry HN Protein - chemistry HN Protein - immunology long chain peptide synthesis Mice Molecular Sequence Data Peptides - chemical synthesis Peptides - immunology Protein Folding respiratory syncytial virus vaccine Respiratory Syncytial Virus Vaccines - administration & dosage Respiratory Syncytial Virus Vaccines - chemistry Respiratory Syncytial Virus Vaccines - immunology Respiratory Syncytial Virus, Human respiratory syncytial virus-G protein Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Viral Envelope Proteins
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