Long-Term Tolerability of Etoricoxib in Patients with Previous Reactions to Non-Steroidal Anti-Inflammatory Drugs

Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Onl...

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Veröffentlicht in:	International journal of immunopathology and pharmacology 2009-10, Vol.22 (4), p.1131-1134
Hauptverfasser:	Di Leo, E., Aloia, A.M., Nettis, E., Cardinale, F., Foti, C., Distaso, M., Ferrannini, A., Vacca, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Aged Aged, 80 and over Anti-Inflammatory Agents, Non-Steroidal - adverse effects Cyclooxygenase 2 Inhibitors - administration & dosage Cyclooxygenase 2 Inhibitors - adverse effects Cyclooxygenase 2 Inhibitors - therapeutic use Drug Hypersensitivity - etiology Female Humans Male Middle Aged Pyridines - administration & dosage Pyridines - adverse effects Pyridines - therapeutic use Retrospective Studies Single-Blind Method Sulfones - administration & dosage Sulfones - adverse effects Sulfones - therapeutic use Young Adult
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Zusammenfassung:	Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Only one of 82 patients who were treated with etoricoxib reported reactions. We can conclude that etoricoxib shows a high long-term tolerability in patients with non-steroidal anti-inflammatory drug hypersensitivity.
ISSN:	0394-6320 2058-7384
DOI:	10.1177/039463200902200431