XPC gene variants: a risk factor for recurrence of urothelial bladder carcinoma in patients on BCG immunotherapy

Purpose To investigate the association between two Xeroderma pigmentosum group C polymorphism (XPC Lys939Gln and insertion/deletion PAT −/+ in intron 9) and bladder cancer (BC) susceptibility. Materials and methods Genotyping was performed in 208 BC patients and 245 controls by PCR-RFLP method. Resu...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2010-05, Vol.136 (5), p.779-786
Hauptverfasser:	Gangwar, Ruchika, Mandhani, Anil, Mittal, Rama Devi
Format:	Artikel
Sprache:	eng
Schlagworte:	Age of Onset Antineoplastic agents Bacterial diseases BCG Vaccine - therapeutic use Biological and medical sciences Bladder Cancer Cancer Research Carcinoma, Transitional Cell - genetics Carcinoma, Transitional Cell - therapy Case-Control Studies DNA-Binding Proteins - genetics Female Genes Genetic Predisposition to Disease Genotype Hematology Human bacterial diseases Humans Immunotherapy Infectious diseases Internal Medicine Male Medical sciences Medicine Medicine & Public Health Middle Aged Nephrology. Urinary tract diseases Oncology Original Paper Pharmacology. Drug treatments Polymorphism, Genetic Risk Factors Tuberculosis and atypical mycobacterial infections Tumors of the urinary system Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - therapy Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland
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