l‐DOPA supply to the neuro retina activates dopaminergic communication at the early stages of embryonic development

DOPA decarboxylase (DDC; aromatic‐l‐amino acid decarboxylase; EC 4.1.1.28) is absent in retinas from 6‐day‐old chicken embryos (E6) but is expressed in retina of E8 embryos, in the presumptive outer plexiform layer. Thereafter, DDC appears in cell bodies of presumptive amacrine cells. The dopamine (...

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Veröffentlicht in:	Journal of neurochemistry 2003-07, Vol.86 (1), p.45-54
Hauptverfasser:	Kubrusly, Regina C. C., Guimarães, Marília Zaluar P., Vieira, Ana Paula B., Hokoç, Jan N., Casarini, Dulce E., De Mello, Maria C. F., De Mello, Fernando G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Communication - drug effects Cell Communication - physiology Chick Embryo DOPA decarboxylase Dopa Decarboxylase - metabolism Dopamine - metabolism Dopamine Agents - metabolism Dopamine Agents - pharmacology dopamine communication embryonic retina Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Immunohistochemistry Levodopa - metabolism Levodopa - pharmacology Neurons - metabolism Neurons - physiology Retina - cytology Retina - drug effects Retina - embryology Retina - metabolism Synaptic Transmission - drug effects Synaptic Transmission - physiology Tyrosine 3-Monooxygenase - biosynthesis Vertebrates: nervous system and sense organs
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