Protective effects of Y-27632 on acute dichlorvos poisoning in rats

Abstract Anticholinesterase poisoning is an important health problem in developing countries, and understanding of its underlying mechanisms is essential for the effective treatment. This study is designed to examine the effects of Y-27632, a selective Rho-kinase inhibitor, on organophosphate-induce...

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Veröffentlicht in:	The American journal of emergency medicine 2010-03, Vol.28 (3), p.268-274
Hauptverfasser:	Gunay, Nurullah, MD, Kose, Beril, MD, Demiryurek, Seniz, PhD, Ceylan, Nurdan Ozlu, MD, Sari, Ibrahim, MD, Demiryurek, Abdullah T., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - pharmacology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Cholinesterase Cholinesterase Inhibitors - poisoning Cholinesterases - blood Creatine Kinase - blood Creatine Kinase, MB Form - blood Developing countries Dichlorvos - poisoning Drug intoxications. Doping Emergency Emergency medical care Enzyme Inhibitors - pharmacology Glutathione - metabolism Immunohistochemistry Intensive care medicine Kinases Laboratory animals LDCs Male Medical sciences Mortality Myoglobin - blood Myoglobins Natriuretic Peptide, Brain - blood Nitric oxide Nitric Oxide - metabolism Oils & fats Organophosphates Peptide Fragments - blood Pesticides Pharmacology. Drug treatments Poisoning Pyridines - pharmacology Random Allocation Rats Rats, Wistar Rodents Statistics, Nonparametric Studies Toxicity Troponin I - blood
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