Diagnostic value of p16INK4A, Ki‐67, and human papillomavirus L1 capsid protein immunochemical staining on cell blocks from residual liquid‐based gynecologic cytology specimens

BACKGROUND: This study was conducted to evaluate the reliability and role of cell block preparations in the diagnosis of neoplastic and preneoplastic lesions of the cervix and to improve the value of cell block preparations in diagnosing and predicting the prognosis of cervical lesions through immun...

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Veröffentlicht in:	Cancer cytopathology 2010-02, Vol.118 (1), p.47-55
Hauptverfasser:	Yu, Li, Wang, Liantang, Zhong, Juemin, Chen, Shangwu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biomarkers, Tumor - analysis Capsid Proteins - metabolism Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - metabolism cell block preparations cervical intraepithelial neoplasia Cervical Intraepithelial Neoplasia - diagnosis Cervical Intraepithelial Neoplasia - metabolism Cyclin-Dependent Kinase Inhibitor p16 - metabolism Cytodiagnosis - methods Female Follow-Up Studies human papillomavirus L1 capsid protein Humans immunocytochemistry Immunoenzyme Techniques Ki-67 Antigen - metabolism Ki‐67 liquid‐based cytology Middle Aged Oncogene Proteins, Viral - metabolism p16INK4A Precancerous Conditions - diagnosis Precancerous Conditions - metabolism Prognosis Uterine Cervical Neoplasms - diagnosis Uterine Cervical Neoplasms - metabolism Vaginal Smears Young Adult
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