Delayed hemolytic transfusion reaction with hyperhemolysis after first red blood cell transfusion in child with β‐thalassemia: challenges in treatment

BACKGROUND: Delayed hemolytic transfusion reaction (DHTR) can manifest with hyperhemolysis, a serious complication of red blood cell (RBC) transfusions. This has mostly been described in sickle cell anemia but occasionally in β‐thalassemia. Treatment is challenging; immunosuppressive medication has...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2010-02, Vol.50 (2), p.429-432
Hauptverfasser:	Hannema, Sabine E., Brand, Anneke, Van Meurs, Alfred, Smiers, Frans J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Hemolytic - drug therapy Anemia, Hemolytic - etiology Anemia, Hemolytic - immunology Anemia, Hemolytic, Autoimmune - drug therapy Anemia, Hemolytic, Autoimmune - etiology Anemia, Hemolytic, Autoimmune - immunology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy beta-Thalassemia - blood beta-Thalassemia - surgery beta-Thalassemia - therapy Biological and medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Bone Marrow Transplantation Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Erythrocyte Transfusion - adverse effects Female Humans Hypersplenism - etiology Hypersplenism - surgery Immunosuppressive Agents - therapeutic use Infant Intensive care medicine Medical sciences Peripheral Blood Stem Cell Transplantation Platelet Transfusion Splenectomy Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation, Homologous
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