Cyclic DGR-peptidomimetic containing a bicyclic reverse turn inducer as a selective alpha(v)beta (5) integrin ligand

3-Aza-6,8-dioxabicyclo[3.2.1]octane-based amino acids as reverse turn inducers have been introduced into cyclic peptidomimetics containing the RGD or DGR retro-sequence, in order to achieve a stereochemical scanning of the binding capability of the resulting molecules towards alpha(v)beta(3) and alp...

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Veröffentlicht in:	Amino acids 2010-01, Vol.38 (1), p.329-337
Hauptverfasser:	Trabocchi, A, Menchi, G, Danieli, E, Potenza, D, Cini, N, Bottoncetti, A, Raspanti, S, Pupi, A, Guarna, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Female Humans Kinetics Ligands Peptides, Cyclic - agonists Peptides, Cyclic - chemical synthesis Peptides, Cyclic - chemistry Placenta - chemistry Placenta - metabolism Pregnancy Protein Binding Receptors, Vitronectin - chemistry Receptors, Vitronectin - metabolism
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