A series of 1, 2-coupled indane dimers with mast cell stabilisation and smooth muscle relaxation properties

Asthma is characterised by bronchoconstriction and inflammation, with infiltration and activation of inflammatory cells such as eosinophils and mast cells, and subsequent release of inflammatory mediators. Much of the therapy directed at the treatment of asthma is either to provide symptomatic relie...

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Veröffentlicht in:European journal of medicinal chemistry 2009-12, Vol.44 (12), p.5018-5022
Hauptverfasser: Sheridan, H., Walsh, J.J., Jordan, M., Cogan, C., Frankish, N.
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Sprache:eng
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