Increased tissue kallikrein levels in type 2 diabetes

Aims/hypothesis We measured components of the kallikrein-kinin system in human type 2 diabetes mellitus and the effects of statin therapy on the circulating kallikrein-kinin system. Methods Circulating levels of bradykinin and kallidin peptides, and high and low molecular weight kininogens, as well...

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Veröffentlicht in:	Diabetologia 2010-04, Vol.53 (4), p.779-785
Hauptverfasser:	Campbell, D. J, Kladis, A, Zhang, Y, Jenkins, A. J, Prior, D. L, Yii, M, Kenny, J. F, Black, M. J, Kelly, D. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - therapeutic use Aspirin Biological and medical sciences Cardiotonic Agents - blood Cardiovascular disease Coronary Artery Bypass Coronary vessels Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - enzymology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - blood Diabetic Angiopathies - drug therapy Diabetic Angiopathies - surgery Endocrine pancreas. Apud cells (diseases) Endocrinopathies Endothelium, Vascular - drug effects Endothelium, Vascular - physiopathology Etiopathogenesis. Screening. Investigations. Target tissue resistance Heart surgery Human Physiology Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypotheses Immunohistochemistry Internal Medicine Medical sciences Medicine Medicine & Public Health Metabolic Diseases Molecular weight Patients Peptides RNA, Messenger - genetics Tissue Kallikreins - blood Tissue Kallikreins - genetics Vein & artery diseases
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