Reactive oxygen species in rostral ventrolateral medulla modulate cardiac sympathetic afferent reflex in rats

The aim of the present study was to investigate whether reactive oxygen species (ROS) in rostral ventrolateral medulla (RVLM) modulate cardiac sympathetic afferent reflex (CSAR) and the enhanced CSAR response caused by microinjection of angiotensin II (Ang II) into the paraventricular nucleus (PVN)....

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Veröffentlicht in:	Acta Physiologica 2009-12, Vol.197 (4), p.297-304
Hauptverfasser:	Zhong, M.-K, Gao, J, Zhang, F, Xu, B, Fan, Z.-D, Wang, W, Zhu, G.-Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetophenones - pharmacology Afferent Pathways - drug effects Afferent Pathways - physiology angiotensin II Angiotensin II - pharmacology Animals Antioxidants - pharmacology Autonomic Pathways - drug effects Autonomic Pathways - physiology Biological and medical sciences Blood Pressure - drug effects Blood Pressure - physiology Capsaicin - pharmacology cardiovascular reflex Cyclic N-Oxides - pharmacology Free Radical Scavengers - pharmacology Fundamental and applied biological sciences. Psychology Heart - innervation Kidney - innervation Male Medulla Oblongata - cytology Medulla Oblongata - drug effects Medulla Oblongata - metabolism NADPH Oxidases - antagonists & inhibitors NADPH Oxidases - metabolism Neuroprotective Agents - pharmacology Paraventricular Hypothalamic Nucleus - drug effects paraventricular nucleus Polyethylene Glycols - pharmacology Random Allocation Rats Rats, Sprague-Dawley reactive oxygen species Reactive Oxygen Species - metabolism Reflex - drug effects Reflex - physiology rostral ventrolateral medulla Sensory System Agents - pharmacology Spin Labels Superoxide Dismutase - antagonists & inhibitors Superoxide Dismutase - metabolism Superoxide Dismutase - pharmacology sympathetic activity Sympathetic Nervous System - drug effects Sympathetic Nervous System - physiology Vasoconstrictor Agents - pharmacology Vertebrates: anatomy and physiology, studies on body, several organs or systems
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