GITR contributes to the systemic adjuvanticity of the Escherichia coli heat‐labile enterotoxin

The Escherichia coli heat‐labile enterotoxin (LT) possesses a powerful mucosal and systemic adjuvant effect. However, little is known about the cellular and molecular basis of the immunostimulatory activity of LT at the mucosal level, and even less information is available on the mechanisms underlyi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of immunology 2010-03, Vol.40 (3), p.754-763
Hauptverfasser:	Tamayo, Esther, Postigo, Jorge, González, Jovanna, Fernández‐Rey, Maigualida, Iglesias, Marcos, Santiuste, Inés, Riccardi, Carlo, Rappuoli, Rino, Del Giudice, Giuseppe, Merino, Ramón, Merino, Jesús
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic Animals Antibodies, Bacterial - immunology Bacterial Toxins - immunology CD4-Positive T-Lymphocytes - immunology Cell Separation Costimulation Enterotoxins - immunology Escherichia coli Proteins - immunology Flow Cytometry Glucocorticoid-Induced TNFR-Related Protein Immunity, Mucosal - immunology Lymphocyte Activation - immunology Mice Mice, Inbred BALB C Mice, Knockout Receptors, Nerve Growth Factor - immunology Receptors, Nerve Growth Factor - metabolism Receptors, Tumor Necrosis Factor - immunology Receptors, Tumor Necrosis Factor - metabolism Reverse Transcriptase Polymerase Chain Reaction T cells Vaccination
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!