Bitter Melon (Momordica charantia) Extract Inhibits Breast Cancer Cell Proliferation by Modulating Cell Cycle Regulatory Genes and Promotes Apoptosis

Breast cancer is one of the most common cancers among women in the United States. Although there are effective drugs for treating advanced stages of breast cancers, women eventually develop resistance. One of the approaches to control breast cancer is prevention through diet, which inhibits one or m...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2010-03, Vol.70 (5), p.1925-1931
Hauptverfasser:	RAY, Ratna B, RAYCHOUDHURI, Amit, STEELE, Robert, NERURKAR, Pratibha
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - antagonists & inhibitors Adaptor Proteins, Signal Transducing - biosynthesis Antineoplastic agents Apoptosis - drug effects Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - pathology Caspases - metabolism Cell Cycle Proteins - antagonists & inhibitors Cell Cycle Proteins - genetics Cell Division - drug effects Cell Division - genetics Cell Growth Processes - drug effects Cell Line, Tumor Enzyme Activation - drug effects Female G2 Phase - drug effects G2 Phase - genetics Genes, cdc - drug effects Gynecology. Andrology. Obstetrics Humans Inhibitor of Apoptosis Proteins Mammary gland diseases Medical sciences Microtubule-Associated Proteins - antagonists & inhibitors Microtubule-Associated Proteins - biosynthesis Momordica charantia - chemistry Pharmacology. Drug treatments Plant Extracts - pharmacology Tumors
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