Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds
Four genes, VTN, KERA, LYZ, and a non-annotated EST (Affymetrix probe set ID: Ssc.25503.1.S1_at), whose candidacy for traits related to water-holding capacity of meat arises from their trait-dependent differential expression, were selected for candidate gene analysis. Based on in silico analysis SNP...
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| Veröffentlicht in: | Molecular biology reports 2010, Vol.37 (1), p.595-601 |
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| description | Four genes, VTN, KERA, LYZ, and a non-annotated EST (Affymetrix probe set ID: Ssc.25503.1.S1_at), whose candidacy for traits related to water-holding capacity of meat arises from their trait-dependent differential expression, were selected for candidate gene analysis. Based on in silico analysis SNPs were detected, confirmed by sequencing and used to genotype animals of 4 pig populations including 3 commercial herds of Pietrain (PI), Pietrain × (German Large White × German Landrace) (PIF1), German Landrace (DL) and 1 experimental F
2
population Duroc × Pietrain (DUPI). Comparative and genetic mapping established the location of VTN on SSC12, of LYZ and KERA on SSC5 and of UN on SSC7, coinciding with QTL regions for meat quality traits. VTN showed association with pH1, pH24 and drip loss. LYZ revealed association with conductivity 24, pH1 and drip loss. KERA was associated with pH. UN showed association with pH24 and drip loss, respectively. However, none of the candidate genes showed significant associations for a particular trait across all populations. This may be due to breed specific effects that are related to the differences in meat quality of theses pig breeds. The studies revealed statistic evidence for a link of genetic variation at these loci or close to them and promoted those four candidate genes as functional and/or positional candidate genes for meat quality traits. |
| doi_str_mv | 10.1007/s11033-009-9856-0 |
| format | Article |
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2
population Duroc × Pietrain (DUPI). Comparative and genetic mapping established the location of VTN on SSC12, of LYZ and KERA on SSC5 and of UN on SSC7, coinciding with QTL regions for meat quality traits. VTN showed association with pH1, pH24 and drip loss. LYZ revealed association with conductivity 24, pH1 and drip loss. KERA was associated with pH. UN showed association with pH24 and drip loss, respectively. However, none of the candidate genes showed significant associations for a particular trait across all populations. This may be due to breed specific effects that are related to the differences in meat quality of theses pig breeds. The studies revealed statistic evidence for a link of genetic variation at these loci or close to them and promoted those four candidate genes as functional and/or positional candidate genes for meat quality traits.</description><identifier>ISSN: 0301-4851</identifier><identifier>EISSN: 1573-4978</identifier><identifier>DOI: 10.1007/s11033-009-9856-0</identifier><identifier>PMID: 19823956</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Animal Anatomy ; Animal Biochemistry ; Animals ; Biological variation ; Biomedical and Life Sciences ; Gene expression ; Gene Expression Regulation ; Gene Frequency ; Haplotypes - genetics ; Histology ; Hogs ; Least-Squares Analysis ; Life Sciences ; Meat - standards ; Molecular biology ; Morphology ; Muscles - metabolism ; Polymorphism ; Pork ; Quantitative Trait Loci - genetics ; Quantitative Trait, Heritable ; Sus scrofa - genetics ; Water - physiology</subject><ispartof>Molecular biology reports, 2010, Vol.37 (1), p.595-601</ispartof><rights>Springer Science+Business Media B.V. 2009</rights><rights>Springer Science+Business Media B.V. 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-46b58a270eeda9b461554f283550e3108a6ac556724f48dbdfd0dcdf05ebcfb73</citedby><cites>FETCH-LOGICAL-c370t-46b58a270eeda9b461554f283550e3108a6ac556724f48dbdfd0dcdf05ebcfb73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11033-009-9856-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11033-009-9856-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19823956$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Srikanchai, Tiranun</creatorcontrib><creatorcontrib>Murani, Eduard</creatorcontrib><creatorcontrib>Wimmers, Klaus</creatorcontrib><creatorcontrib>Ponsuksili, Siriluck</creatorcontrib><title>Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds</title><title>Molecular biology reports</title><addtitle>Mol Biol Rep</addtitle><addtitle>Mol Biol Rep</addtitle><description>Four genes, VTN, KERA, LYZ, and a non-annotated EST (Affymetrix probe set ID: Ssc.25503.1.S1_at), whose candidacy for traits related to water-holding capacity of meat arises from their trait-dependent differential expression, were selected for candidate gene analysis. Based on in silico analysis SNPs were detected, confirmed by sequencing and used to genotype animals of 4 pig populations including 3 commercial herds of Pietrain (PI), Pietrain × (German Large White × German Landrace) (PIF1), German Landrace (DL) and 1 experimental F
2
population Duroc × Pietrain (DUPI). Comparative and genetic mapping established the location of VTN on SSC12, of LYZ and KERA on SSC5 and of UN on SSC7, coinciding with QTL regions for meat quality traits. VTN showed association with pH1, pH24 and drip loss. LYZ revealed association with conductivity 24, pH1 and drip loss. KERA was associated with pH. UN showed association with pH24 and drip loss, respectively. However, none of the candidate genes showed significant associations for a particular trait across all populations. This may be due to breed specific effects that are related to the differences in meat quality of theses pig breeds. The studies revealed statistic evidence for a link of genetic variation at these loci or close to them and promoted those four candidate genes as functional and/or positional candidate genes for meat quality traits.</description><subject>Animal Anatomy</subject><subject>Animal Biochemistry</subject><subject>Animals</subject><subject>Biological variation</subject><subject>Biomedical and Life Sciences</subject><subject>Gene expression</subject><subject>Gene Expression Regulation</subject><subject>Gene Frequency</subject><subject>Haplotypes - genetics</subject><subject>Histology</subject><subject>Hogs</subject><subject>Least-Squares Analysis</subject><subject>Life Sciences</subject><subject>Meat - standards</subject><subject>Molecular biology</subject><subject>Morphology</subject><subject>Muscles - metabolism</subject><subject>Polymorphism</subject><subject>Pork</subject><subject>Quantitative Trait Loci - genetics</subject><subject>Quantitative Trait, Heritable</subject><subject>Sus scrofa - genetics</subject><subject>Water - physiology</subject><issn>0301-4851</issn><issn>1573-4978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kc-KFDEQh4Mo7uzqA3iR4MVTtNLpdNJHWXZ1YcGLnkM6qZ7Jkv6zSTfrvIWPbNoZUARPBamvvgr1I-QNhw8cQH3MnIMQDKBlrZYNg2dkx6USrG6Vfk52IICzWkt-QS5zfgCAmiv5klzwVleilc2O_Lyd1kTj5AL1oe8x4bgEG-OR4o85Yc7oaRjpsGYXkS4h5xWpxxlHH8Y9nUb6ZBdM7DDF3w_OztaF5UhtQmpzLuLS9_QpLAc6oF3o42rjBhSrm4YBUyEincOeHjD5_Iq86G3M-Ppcr8j325tv11_Y_dfPd9ef7pkTChZWN53UtlKA6G3b1Q2Xsu4rLaQEFBy0bayTslFV3dfad7734J3vQWLn-k6JK_L-5J3T9LhiXswQssMY7YjTmo0SotFai4189w_5UG42ls-ZcscaGiU3iJ8gl6acE_ZmTmGw6Wg4mC0scwrLlLDMFpaBMvP2LF67Af2fiXM6BahOQC6tcY_pr83_tf4CY7Wihw</recordid><startdate>2010</startdate><enddate>2010</enddate><creator>Srikanchai, Tiranun</creator><creator>Murani, Eduard</creator><creator>Wimmers, Klaus</creator><creator>Ponsuksili, Siriluck</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>2010</creationdate><title>Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds</title><author>Srikanchai, Tiranun ; Murani, Eduard ; Wimmers, Klaus ; Ponsuksili, Siriluck</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-46b58a270eeda9b461554f283550e3108a6ac556724f48dbdfd0dcdf05ebcfb73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Animal Anatomy</topic><topic>Animal Biochemistry</topic><topic>Animals</topic><topic>Biological variation</topic><topic>Biomedical and Life Sciences</topic><topic>Gene expression</topic><topic>Gene Expression Regulation</topic><topic>Gene Frequency</topic><topic>Haplotypes - genetics</topic><topic>Histology</topic><topic>Hogs</topic><topic>Least-Squares Analysis</topic><topic>Life Sciences</topic><topic>Meat - standards</topic><topic>Molecular biology</topic><topic>Morphology</topic><topic>Muscles - metabolism</topic><topic>Polymorphism</topic><topic>Pork</topic><topic>Quantitative Trait Loci - genetics</topic><topic>Quantitative Trait, Heritable</topic><topic>Sus scrofa - genetics</topic><topic>Water - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Srikanchai, Tiranun</creatorcontrib><creatorcontrib>Murani, Eduard</creatorcontrib><creatorcontrib>Wimmers, Klaus</creatorcontrib><creatorcontrib>Ponsuksili, Siriluck</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular biology reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Srikanchai, Tiranun</au><au>Murani, Eduard</au><au>Wimmers, Klaus</au><au>Ponsuksili, Siriluck</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds</atitle><jtitle>Molecular biology reports</jtitle><stitle>Mol Biol Rep</stitle><addtitle>Mol Biol Rep</addtitle><date>2010</date><risdate>2010</risdate><volume>37</volume><issue>1</issue><spage>595</spage><epage>601</epage><pages>595-601</pages><issn>0301-4851</issn><eissn>1573-4978</eissn><abstract>Four genes, VTN, KERA, LYZ, and a non-annotated EST (Affymetrix probe set ID: Ssc.25503.1.S1_at), whose candidacy for traits related to water-holding capacity of meat arises from their trait-dependent differential expression, were selected for candidate gene analysis. Based on in silico analysis SNPs were detected, confirmed by sequencing and used to genotype animals of 4 pig populations including 3 commercial herds of Pietrain (PI), Pietrain × (German Large White × German Landrace) (PIF1), German Landrace (DL) and 1 experimental F
2
population Duroc × Pietrain (DUPI). Comparative and genetic mapping established the location of VTN on SSC12, of LYZ and KERA on SSC5 and of UN on SSC7, coinciding with QTL regions for meat quality traits. VTN showed association with pH1, pH24 and drip loss. LYZ revealed association with conductivity 24, pH1 and drip loss. KERA was associated with pH. UN showed association with pH24 and drip loss, respectively. However, none of the candidate genes showed significant associations for a particular trait across all populations. This may be due to breed specific effects that are related to the differences in meat quality of theses pig breeds. The studies revealed statistic evidence for a link of genetic variation at these loci or close to them and promoted those four candidate genes as functional and/or positional candidate genes for meat quality traits.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>19823956</pmid><doi>10.1007/s11033-009-9856-0</doi><tpages>7</tpages></addata></record> |
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| subjects | Animal Anatomy Animal Biochemistry Animals Biological variation Biomedical and Life Sciences Gene expression Gene Expression Regulation Gene Frequency Haplotypes - genetics Histology Hogs Least-Squares Analysis Life Sciences Meat - standards Molecular biology Morphology Muscles - metabolism Polymorphism Pork Quantitative Trait Loci - genetics Quantitative Trait, Heritable Sus scrofa - genetics Water - physiology |
| title | Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds |
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