Challenging diagnosis of ileal gastrointestinal stromal tumor presenting with obscure digestive bleeding

We report a case of a patient observed in emergency condition for recurrent episodes of massive obscure gastrointestinal bleeding that required surgical control. At laparotomy we found an ileal mass with the characteristics of a gastrointestinal stromal tumor (GIST) at histopathological analysis. GI...

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Veröffentlicht in:Tumori 2009-11, Vol.95 (6), p.823-827
Hauptverfasser: Degrate, Luca, Nobili, Cinzia, Garancini, Mattia, Scotti, Mauro Alessandro, Scotti, Marco, Romano, Fabrizio, Franciosi, Claudio, Caprotti, Roberto, Uggeri, Franco
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container_end_page 827
container_issue 6
container_start_page 823
container_title Tumori
container_volume 95
creator Degrate, Luca
Nobili, Cinzia
Garancini, Mattia
Scotti, Mauro Alessandro
Scotti, Marco
Romano, Fabrizio
Franciosi, Claudio
Caprotti, Roberto
Uggeri, Franco
description We report a case of a patient observed in emergency condition for recurrent episodes of massive obscure gastrointestinal bleeding that required surgical control. At laparotomy we found an ileal mass with the characteristics of a gastrointestinal stromal tumor (GIST) at histopathological analysis. GISTs should always be considered as a possible cause of obscure gastrointestinal bleeding, although they are often difficult to diagnose preoperatively. Laparotomy is sometimes the only way to obtain a diagnosis. Starting from this case, we reviewed the literature about GISTs, focusing our attention on their diagnosis and the possible surgical and nonsurgical therapies.
doi_str_mv 10.1177/030089160909500630
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subjects Antineoplastic Agents - therapeutic use
Benzamides
Diagnosis, Differential
Gastrointestinal Hemorrhage - etiology
Gastrointestinal Hemorrhage - surgery
Gastrointestinal Stromal Tumors - complications
Gastrointestinal Stromal Tumors - diagnosis
Gastrointestinal Stromal Tumors - secondary
Gastrointestinal Stromal Tumors - surgery
Humans
Ileal Neoplasms - complications
Ileal Neoplasms - diagnosis
Ileal Neoplasms - pathology
Ileal Neoplasms - surgery
Imatinib Mesylate
Laparotomy
Lung Neoplasms - diagnosis
Lung Neoplasms - drug therapy
Lung Neoplasms - secondary
Male
Middle Aged
Neoplasm Recurrence, Local - drug therapy
Piperazines - therapeutic use
Pyrimidines - therapeutic use
Treatment Outcome
title Challenging diagnosis of ileal gastrointestinal stromal tumor presenting with obscure digestive bleeding
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