Cytochrome c oxidase is regulated by modulations in protein expression and mitochondrial membrane phospholipid composition in estivating African lungfish

We examined some of the potential mechanisms lungfish (Protopterus dolloi) use to regulate cytochrome c oxidase (CCO), during metabolic depression. CCO activity was reduced by 67% in isolated liver mitochondria of estivating fish. This was likely accomplished, in part, by the 46% reduction in CCO su...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2010-03, Vol.298 (3), p.R608-R616
Hauptverfasser:	Frick, N T, Bystriansky, J S, Ip, Y K, Chew, S F, Ballantyne, J S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Cardiolipins - metabolism Electron Transport Complex IV - genetics Electron Transport Complex IV - metabolism Energy Metabolism - physiology Estivation - physiology Fish Fishes - physiology Gene Expression Regulation, Enzymologic - physiology Lipids Liver - metabolism Membranes Mitochondria Mitochondria - enzymology Mitochondrial Membranes - metabolism Oxidation Oxygen Proteins Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism
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