Sperm immobilizing antibodies react to the 3- O-sulfated galactose residue of seminolipid on human sperm

It is well known that very few women who possess sperm immobilizing antibodies in their sera can conceive naturally even though there are no abnormalities in their reproductive organs on routine medical examination. A monoclonal antibody (MAb), designated 2H12, was produced by immunizing a BALB/c mo...

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Veröffentlicht in:	Journal of reproductive immunology 1992-10, Vol.22 (3), p.225-236
Hauptverfasser:	Tsuji, Yoshiyuki, Fukuda, Hiroshi, Iuchi, Akiko, Ishizuka, Ineo, Isojima, Shinzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antigens, Surface - immunology Biological and medical sciences Birth control Choriocarcinoma - immunology Epitopes - immunology Female Galactose - analogs & derivatives Galactose - immunology Glycolipids - immunology Gynecology. Andrology. Obstetrics Humans Infertility, Female - immunology Isoantibodies - immunology Male Medical sciences Mice Mice, Inbred BALB C - immunology Microspheres Spermatozoa - immunology Sterility. Assisted procreation Tumor Cells, Cultured Uterine Neoplasms - immunology
Online-Zugang:	Volltext
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