Plasma interleukin-2 levels and thyroid function in elderly patients with nonthyroidal illness

Plasma interleukin-2 levels and thyroid function in elderly patients with nonthyroidal illness

To determine whether interleukin-2 (IL-2) plasma concentrations are modified in patients with nonthyroidal illness (NTI) and thyroid function alterations, we measured plasma concentrations of T 3, T 4, free T 3 (FT 3), free T 4 (FT 4), TSH, and IL-2 in 34 elderly NTI patients and in 25 age- and sex-...

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Veröffentlicht in:Archives of gerontology and geriatrics 1998-05, Vol.26 (3), p.275-282
Hauptverfasser: Allegra, A, Corica, F, Buemi, M, Corsonello, A, Rubino, F, Raffaele Addamo, F, Bonanzinga, S, Nicita Mauro, V, Ceruso, D
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Sprache:eng
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Aging
Interleukin-2
Low T 3 syndrome
Nonthyroidal illness
Thyroid
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container_end_page 282
container_issue 3
container_start_page 275
container_title Archives of gerontology and geriatrics
container_volume 26
creator Allegra, A
Corica, F
Buemi, M
Corsonello, A
Rubino, F
Raffaele Addamo, F
Bonanzinga, S
Nicita Mauro, V
Ceruso, D
description To determine whether interleukin-2 (IL-2) plasma concentrations are modified in patients with nonthyroidal illness (NTI) and thyroid function alterations, we measured plasma concentrations of T 3, T 4, free T 3 (FT 3), free T 4 (FT 4), TSH, and IL-2 in 34 elderly NTI patients and in 25 age- and sex-matched healthy controls. IL-2 was detectable in 11 of the 34 patients. Patients with detectable IL-2 plasma levels had significantly lower plasma T 3 and FT 3 concentrations when compared to those with undetectable IL-2. Moreover, IL-2 plasma levels were positively correlated to reverse T 3 (rT 3), ( r S=0.67, P
doi_str_mv 10.1016/S0167-4943(98)00010-7
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IL-2 was detectable in 11 of the 34 patients. Patients with detectable IL-2 plasma levels had significantly lower plasma T 3 and FT 3 concentrations when compared to those with undetectable IL-2. Moreover, IL-2 plasma levels were positively correlated to reverse T 3 (rT 3), ( r S=0.67, P&lt;0.05), and negatively to FT 3 concentrations ( r S =−0.64, P&lt;0.05). 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subjects Aging
Interleukin-2
Low T 3 syndrome
Nonthyroidal illness
Thyroid
title Plasma interleukin-2 levels and thyroid function in elderly patients with nonthyroidal illness
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