Hollow fiber bioartificial liver utilizing collagen-entrapped porcine hepatocyte spheroids

A xenogeneic hollow fiber bioreactor utilizing collagen‐entrapped dispersed hepatocytes has been developed as an extracorporeal bioartificial liver (BAL) for potential treatment of acute human fulminant hepatitis. Prolonged viability, enhanced liver‐specific functions, and differentiated state have...

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Veröffentlicht in:	Biotechnology and bioengineering 1996-10, Vol.52 (1), p.34-44
Hauptverfasser:	Wu, Florence J., Friend, Julie R., Lazar, Arye, Mann, Henry J., Remmel, Rory P., Cerra, Frank B., Hu, Wei-Shou
Format:	Artikel
Sprache:	eng
Schlagworte:	albumin synthesis Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy bioartificial liver Biological and medical sciences bioreactor collagen Emergency and intensive care: digestive diseases. Bioartificial liver glucuronidation hepatocyte spheroid hollow fiber Intensive care medicine Medical sciences porcine hepatocyte ureagenesis
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