Use of comparative reasoning tools for evaluation of the effect of sterilization conditions on fermentations to produce acidic fibroblast growth factor

The effects of various medium sterilization conditions on fermentations of a recombinant, acidic fibroblast growth factor (aFGF) producing Escherichia coli have been studied. Changes in the medium resulting from sterilization were monitored by pH and absorption spectra. This simple experiment provid...

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Veröffentlicht in:Biotechnology and bioengineering 1995-09, Vol.47 (6), p.688-695
Hauptverfasser: Marshall, Carolynne T., Lilly, Malcolm D., Gbewonyo, Kodzo, Buckland, Barry C.
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Sprache:eng
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