Synthesis of 2-Boryl- and Silylindoles by Copper-Catalyzed Borylative and Silylative Cyclization of 2-Alkenylaryl Isocyanides

We have developed a method for the synthesis of 2-borylindoles via the copper(I)-catalyzed borylative cyclization of 2-alkenylphenyl isocyanides using diboronate. The reaction proceeds at room temperature under neutral conditions and exhibits high tolerance to functional groups, such as Br, CO2R, CO...

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Veröffentlicht in:	Journal of organic chemistry 2010-07, Vol.75 (14), p.4841-4847
Hauptverfasser:	Tobisu, Mamoru, Fujihara, Hirokazu, Koh, Keika, Chatani, Naoto
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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