Efficacy of bleeding control using a large amount of highly diluted vasopressin in laparoscopic treatment for interstitial pregnancy

Objective We sought to report the safety and effectiveness of bleeding control using a large amount of highly diluted vasopressin in laparoscopic management of interstitial pregnancy. Study Design This was an uncontrolled retrospective review of 20 patients who were laparoscopically treated for inte...

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Veröffentlicht in:American journal of obstetrics and gynecology 2010-07, Vol.203 (1), p.30.e1-30.e6
Hauptverfasser: Moon, Hwa Sook, MD, PhD, Kim, Sang Gab, MD, PhD, Park, Gun Sik, MD, Choi, Jin Kuk, MD, Koo, Ja Seong, MD, Joo, Bo Sun, PhD
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container_end_page 30.e6
container_issue 1
container_start_page 30.e1
container_title American journal of obstetrics and gynecology
container_volume 203
creator Moon, Hwa Sook, MD, PhD
Kim, Sang Gab, MD, PhD
Park, Gun Sik, MD
Choi, Jin Kuk, MD
Koo, Ja Seong, MD
Joo, Bo Sun, PhD
description Objective We sought to report the safety and effectiveness of bleeding control using a large amount of highly diluted vasopressin in laparoscopic management of interstitial pregnancy. Study Design This was an uncontrolled retrospective review of 20 patients who were laparoscopically treated for interstitial pregnancy using a large amount of highly diluted vasopressin. For hemostasis, 1 ampule of vasopressin was diluted in 1000 mL of normal saline (1000-fold) and 150-250 mL of diluted vasopressin was injected in the uterus below interstitial pregnancy. Results Mean patient age and gestational age was 33.5 years and 6.7 weeks, respectively. Mean blood loss was 24 mL. The mean serum human chorionic gonadotropin level was 10,950, 4065, and 959 mIU/mL on the day of operation and postoperative days 1 and 4, respectively. Conclusion Laparoscopic management of interstitial pregnancy using a large amount of highly diluted vasopressin is safe and effective in hemostasis with minimal blood loss and no complications.
doi_str_mv 10.1016/j.ajog.2010.02.030
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Study Design This was an uncontrolled retrospective review of 20 patients who were laparoscopically treated for interstitial pregnancy using a large amount of highly diluted vasopressin. For hemostasis, 1 ampule of vasopressin was diluted in 1000 mL of normal saline (1000-fold) and 150-250 mL of diluted vasopressin was injected in the uterus below interstitial pregnancy. Results Mean patient age and gestational age was 33.5 years and 6.7 weeks, respectively. Mean blood loss was 24 mL. The mean serum human chorionic gonadotropin level was 10,950, 4065, and 959 mIU/mL on the day of operation and postoperative days 1 and 4, respectively. Conclusion Laparoscopic management of interstitial pregnancy using a large amount of highly diluted vasopressin is safe and effective in hemostasis with minimal blood loss and no complications.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/j.ajog.2010.02.030</identifier><identifier>PMID: 20451893</identifier><identifier>CODEN: AJOGAH</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adult ; Biological and medical sciences ; Digestive system. Abdomen ; Diseases of mother, fetus and pregnancy ; endoloop ligation ; Endoscopy ; Female ; Gynecology. Andrology. Obstetrics ; hemostasis ; Hemostasis, Surgical - methods ; highly diluted vasopressin ; Humans ; interstitial pregnancy ; Investigative techniques, diagnostic techniques (general aspects) ; laparoscopic operation ; Laparoscopy - methods ; Medical sciences ; Obstetrics and Gynecology ; Pregnancy ; Pregnancy, Ectopic - surgery ; Pregnancy. Fetus. Placenta ; Retrospective Studies ; Vasoconstrictor Agents - administration &amp; dosage ; Vasopressins - administration &amp; dosage</subject><ispartof>American journal of obstetrics and gynecology, 2010-07, Vol.203 (1), p.30.e1-30.e6</ispartof><rights>Mosby, Inc.</rights><rights>2010 Mosby, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright (c) 2010 Mosby, Inc. 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Study Design This was an uncontrolled retrospective review of 20 patients who were laparoscopically treated for interstitial pregnancy using a large amount of highly diluted vasopressin. For hemostasis, 1 ampule of vasopressin was diluted in 1000 mL of normal saline (1000-fold) and 150-250 mL of diluted vasopressin was injected in the uterus below interstitial pregnancy. Results Mean patient age and gestational age was 33.5 years and 6.7 weeks, respectively. Mean blood loss was 24 mL. The mean serum human chorionic gonadotropin level was 10,950, 4065, and 959 mIU/mL on the day of operation and postoperative days 1 and 4, respectively. Conclusion Laparoscopic management of interstitial pregnancy using a large amount of highly diluted vasopressin is safe and effective in hemostasis with minimal blood loss and no complications.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Digestive system. Abdomen</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>endoloop ligation</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>hemostasis</subject><subject>Hemostasis, Surgical - methods</subject><subject>highly diluted vasopressin</subject><subject>Humans</subject><subject>interstitial pregnancy</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>laparoscopic operation</subject><subject>Laparoscopy - methods</subject><subject>Medical sciences</subject><subject>Obstetrics and Gynecology</subject><subject>Pregnancy</subject><subject>Pregnancy, Ectopic - surgery</subject><subject>Pregnancy. Fetus. 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Abdomen</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>endoloop ligation</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>hemostasis</topic><topic>Hemostasis, Surgical - methods</topic><topic>highly diluted vasopressin</topic><topic>Humans</topic><topic>interstitial pregnancy</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>laparoscopic operation</topic><topic>Laparoscopy - methods</topic><topic>Medical sciences</topic><topic>Obstetrics and Gynecology</topic><topic>Pregnancy</topic><topic>Pregnancy, Ectopic - surgery</topic><topic>Pregnancy. Fetus. 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subjects Adult
Biological and medical sciences
Digestive system. Abdomen
Diseases of mother, fetus and pregnancy
endoloop ligation
Endoscopy
Female
Gynecology. Andrology. Obstetrics
hemostasis
Hemostasis, Surgical - methods
highly diluted vasopressin
Humans
interstitial pregnancy
Investigative techniques, diagnostic techniques (general aspects)
laparoscopic operation
Laparoscopy - methods
Medical sciences
Obstetrics and Gynecology
Pregnancy
Pregnancy, Ectopic - surgery
Pregnancy. Fetus. Placenta
Retrospective Studies
Vasoconstrictor Agents - administration & dosage
Vasopressins - administration & dosage
title Efficacy of bleeding control using a large amount of highly diluted vasopressin in laparoscopic treatment for interstitial pregnancy
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