ELAC2/HPC2 Polymorphisms, Prostate-Specific Antigen Levels, and Prostate Cancer

Background: The ELAC2 gene has been proposed to be a prostate cancer susceptibility gene and is being referred to as HPC2, in part because three case–control studies suggested that two common polymorphisms (Ser217Leu and Ala541Thr) are associated with risk. However, four subsequent larger studies ha...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2003-06, Vol.95 (11), p.818-824
Hauptverfasser:	Severi, Gianluca, Giles, Graham G., Southey, Melissa C., Tesoriero, Andrea, Tilley, Wayne, Neufing, Petra, Morris, Howard, English, Dallas R., McCredie, Margaret R. E., Boyle, Peter, Hopper, John L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alanine - genetics Biological and medical sciences Case-Control Studies Genetic Predisposition to Disease Heterozygote Homozygote Humans Leucine - genetics Linear Models Logistic Models Male Medical sciences Middle Aged Neoplasm Proteins - genetics Nephrology. Urinary tract diseases Odds Ratio Polymorphism, Genetic Prostate-Specific Antigen - blood Prostatic Neoplasms - genetics Prostatic Neoplasms - immunology Research Design Risk Assessment Risk Factors Serine - genetics Threonine - genetics Tropical medicine Tumors of the urinary system Urinary tract. Prostate gland
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