ADAMTS‐13 assays in thrombotic thrombocytopenic purpura

ADAMTS‐13, the thirteenth member of the ADAMTS (A Disintegrin And Metalloprotease with Thrombo‐Spondin 1 repeats) family, is the plasma metalloprotease responsible for regulating the multimeric structure of VWF. In congenital or acquired deficiency it is actively involved in the pathophysiology of t...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2010-04, Vol.8 (4), p.631-640
Hauptverfasser:	PEYVANDI, F., PALLA, R., LOTTA, L. A., MACKIE, I., SCULLY, M. A., MACHIN, S. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins - blood ADAM Proteins - deficiency ADAM Proteins - genetics ADAM Proteins - immunology ADAMTS13 Protein ADAMTS‐13 assays Autoantibodies - blood Biomarkers - blood Clinical Enzyme Tests - standards clinical utility Diagnosis, Differential Humans Immunoassay - standards Predictive Value of Tests Purpura, Thrombotic Thrombocytopenic - diagnosis Purpura, Thrombotic Thrombocytopenic - enzymology Purpura, Thrombotic Thrombocytopenic - genetics Purpura, Thrombotic Thrombocytopenic - immunology Reagent Kits, Diagnostic standardization
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