Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital
Please cite this paper as: van de Vijver A, Poppe W, Verguts J, Arbyn M. Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital. BJOG 2010;117:268–273. Objective To assess pregnancy outcome after conisation. Design Retrospective cohort study. Se...
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| creator | van de Vijver, A Poppe, W Verguts, J Arbyn, M |
| description | Please cite this paper as: van de Vijver A, Poppe W, Verguts J, Arbyn M. Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital. BJOG 2010;117:268–273.
Objective To assess pregnancy outcome after conisation.
Design Retrospective cohort study.
Setting Belgium, data from a university hospital.
Population Fifty‐five pregnancies in 34 women after conisation, and 55 pregnancies in 54 women without a history of conisation or cervical intraepithelial neoplasia (CIN).
Methods Hospital data were reviewed and questionnaires were collected from 599 women who had a conisation in a 5‐year period, among whom subsequent pregnancies were identified. The control group consisted of matched pregnancies of women without a history of conisation.
Main outcome measures Gestational age at delivery, neonatal biometry, neonatal condition at birth.
Results Numbers of sexual partners (4.6 ± 3.4 SD versus 2.5 ± 2.5 SD) and ex‐smokers were significantly higher in the study group compared with the control group. Gestational age at delivery (266 ± 2 days versus 274 ± 9 days), neonatal head circumference (33.9 ± 2.5 cm, versus 34.6 ± 2.5 cm) and birthweight (3088 ± 754 g versus 3381 ± 430 g) were significantly lower in the study group compared with the control group. Numbers of preterm [ |
| doi_str_mv | 10.1111/j.1471-0528.2009.02437.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733645172</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733645172</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4647-eeab10cff70fb44390c9b02310e72b34bc30774b48458d7712c1fb2e115dd30a3</originalsourceid><addsrcrecordid>eNqNkE1P3DAQhq2qqFDgLyBfqp6Sjj-yTpB6AFRK0Ur0UM6W40zASzZZbGdL_j0Ou6LX-jIjzfPanocQyiBn6Xxb5UwqlkHBy5wDVDlwKVT-8oEcvQ8-vvWQgeDlIfkcwgqALTiIT-SQVZUUJZdH5Om3x4fe9HaiwxjtsEZq2oieWvRbZ01H7dC7YKIb-nNqqMfoh7BBG90W0-xx8JGGODYTdT2Nj0iXOG6xp_d9AnxwcaI3KeCi6U7IQWu6gKf7ekzur3_8ubrJlnc_f11dLDMrF1JliKZmYNtWQVtLKSqwVQ1cMEDFayFrK0ApWctSFmWjFOOWtTVHxoqmEWDEMfm6u3fjh-cRQ9RrFyx2nelxGINWQixkwRRPZLkjbVoqeGz1xru18ZNmoGfTeqVnoXoWqmfT-s20fknRs_0jY73G5l9wrzYBX_aACclj65NkF945zrkqWMUS933H_XUdTv_9AX15ezd34hXBKprk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733645172</pqid></control><display><type>article</type><title>Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>van de Vijver, A ; Poppe, W ; Verguts, J ; Arbyn, M</creator><creatorcontrib>van de Vijver, A ; Poppe, W ; Verguts, J ; Arbyn, M</creatorcontrib><description>Please cite this paper as: van de Vijver A, Poppe W, Verguts J, Arbyn M. Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital. BJOG 2010;117:268–273.
Objective To assess pregnancy outcome after conisation.
Design Retrospective cohort study.
Setting Belgium, data from a university hospital.
Population Fifty‐five pregnancies in 34 women after conisation, and 55 pregnancies in 54 women without a history of conisation or cervical intraepithelial neoplasia (CIN).
Methods Hospital data were reviewed and questionnaires were collected from 599 women who had a conisation in a 5‐year period, among whom subsequent pregnancies were identified. The control group consisted of matched pregnancies of women without a history of conisation.
Main outcome measures Gestational age at delivery, neonatal biometry, neonatal condition at birth.
Results Numbers of sexual partners (4.6 ± 3.4 SD versus 2.5 ± 2.5 SD) and ex‐smokers were significantly higher in the study group compared with the control group. Gestational age at delivery (266 ± 2 days versus 274 ± 9 days), neonatal head circumference (33.9 ± 2.5 cm, versus 34.6 ± 2.5 cm) and birthweight (3088 ± 754 g versus 3381 ± 430 g) were significantly lower in the study group compared with the control group. Numbers of preterm [<37 weeks; 14/55 (25%) versus 2/55 (4%); P = 0.002] and severe preterm (<34 weeks; 6/55 (11%) versus 0/55 (0%); P = 0.031] deliveries in the study group were significantly higher. There were no cases of perinatal mortality.
Conclusions Conisation affects obstetrical outcome after conisation for CIN. Babies tend to be born earlier and are smaller. It is not clear whether this is related to the procedure or to factors linked with CIN.</description><identifier>ISSN: 1470-0328</identifier><identifier>EISSN: 1471-0528</identifier><identifier>DOI: 10.1111/j.1471-0528.2009.02437.x</identifier><identifier>PMID: 19943824</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Biological and medical sciences ; Birth Weight ; Cephalometry ; Cervical intraepithelial neoplasia ; Cervical Intraepithelial Neoplasia - pathology ; Cervical Intraepithelial Neoplasia - surgery ; conisation ; Conization - adverse effects ; Female ; Gestational Age ; Gynecology. Andrology. Obstetrics ; Head - anatomy & histology ; Humans ; Infant, Newborn ; Male ; Medical sciences ; Obstetric Labor, Premature - etiology ; Pregnancy ; Pregnancy Outcome ; prematurity ; Retrospective Studies ; Sexual Behavior - statistics & numerical data ; Uterine Cervical Neoplasms - pathology ; Uterine Cervical Neoplasms - surgery</subject><ispartof>BJOG : an international journal of obstetrics and gynaecology, 2010-02, Vol.117 (3), p.268-273</ispartof><rights>2009 The Authors Journal compilation © RCOG 2009 BJOG An International Journal of Obstetrics and Gynaecology</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4647-eeab10cff70fb44390c9b02310e72b34bc30774b48458d7712c1fb2e115dd30a3</citedby><cites>FETCH-LOGICAL-c4647-eeab10cff70fb44390c9b02310e72b34bc30774b48458d7712c1fb2e115dd30a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1471-0528.2009.02437.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1471-0528.2009.02437.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22275191$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19943824$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van de Vijver, A</creatorcontrib><creatorcontrib>Poppe, W</creatorcontrib><creatorcontrib>Verguts, J</creatorcontrib><creatorcontrib>Arbyn, M</creatorcontrib><title>Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital</title><title>BJOG : an international journal of obstetrics and gynaecology</title><addtitle>BJOG</addtitle><description>Please cite this paper as: van de Vijver A, Poppe W, Verguts J, Arbyn M. Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital. BJOG 2010;117:268–273.
Objective To assess pregnancy outcome after conisation.
Design Retrospective cohort study.
Setting Belgium, data from a university hospital.
Population Fifty‐five pregnancies in 34 women after conisation, and 55 pregnancies in 54 women without a history of conisation or cervical intraepithelial neoplasia (CIN).
Methods Hospital data were reviewed and questionnaires were collected from 599 women who had a conisation in a 5‐year period, among whom subsequent pregnancies were identified. The control group consisted of matched pregnancies of women without a history of conisation.
Main outcome measures Gestational age at delivery, neonatal biometry, neonatal condition at birth.
Results Numbers of sexual partners (4.6 ± 3.4 SD versus 2.5 ± 2.5 SD) and ex‐smokers were significantly higher in the study group compared with the control group. Gestational age at delivery (266 ± 2 days versus 274 ± 9 days), neonatal head circumference (33.9 ± 2.5 cm, versus 34.6 ± 2.5 cm) and birthweight (3088 ± 754 g versus 3381 ± 430 g) were significantly lower in the study group compared with the control group. Numbers of preterm [<37 weeks; 14/55 (25%) versus 2/55 (4%); P = 0.002] and severe preterm (<34 weeks; 6/55 (11%) versus 0/55 (0%); P = 0.031] deliveries in the study group were significantly higher. There were no cases of perinatal mortality.
Conclusions Conisation affects obstetrical outcome after conisation for CIN. Babies tend to be born earlier and are smaller. It is not clear whether this is related to the procedure or to factors linked with CIN.</description><subject>Biological and medical sciences</subject><subject>Birth Weight</subject><subject>Cephalometry</subject><subject>Cervical intraepithelial neoplasia</subject><subject>Cervical Intraepithelial Neoplasia - pathology</subject><subject>Cervical Intraepithelial Neoplasia - surgery</subject><subject>conisation</subject><subject>Conization - adverse effects</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Head - anatomy & histology</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Obstetric Labor, Premature - etiology</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>prematurity</subject><subject>Retrospective Studies</subject><subject>Sexual Behavior - statistics & numerical data</subject><subject>Uterine Cervical Neoplasms - pathology</subject><subject>Uterine Cervical Neoplasms - surgery</subject><issn>1470-0328</issn><issn>1471-0528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1P3DAQhq2qqFDgLyBfqp6Sjj-yTpB6AFRK0Ur0UM6W40zASzZZbGdL_j0Ou6LX-jIjzfPanocQyiBn6Xxb5UwqlkHBy5wDVDlwKVT-8oEcvQ8-vvWQgeDlIfkcwgqALTiIT-SQVZUUJZdH5Om3x4fe9HaiwxjtsEZq2oieWvRbZ01H7dC7YKIb-nNqqMfoh7BBG90W0-xx8JGGODYTdT2Nj0iXOG6xp_d9AnxwcaI3KeCi6U7IQWu6gKf7ekzur3_8ubrJlnc_f11dLDMrF1JliKZmYNtWQVtLKSqwVQ1cMEDFayFrK0ApWctSFmWjFOOWtTVHxoqmEWDEMfm6u3fjh-cRQ9RrFyx2nelxGINWQixkwRRPZLkjbVoqeGz1xru18ZNmoGfTeqVnoXoWqmfT-s20fknRs_0jY73G5l9wrzYBX_aACclj65NkF945zrkqWMUS933H_XUdTv_9AX15ezd34hXBKprk</recordid><startdate>201002</startdate><enddate>201002</enddate><creator>van de Vijver, A</creator><creator>Poppe, W</creator><creator>Verguts, J</creator><creator>Arbyn, M</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201002</creationdate><title>Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital</title><author>van de Vijver, A ; Poppe, W ; Verguts, J ; Arbyn, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4647-eeab10cff70fb44390c9b02310e72b34bc30774b48458d7712c1fb2e115dd30a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Biological and medical sciences</topic><topic>Birth Weight</topic><topic>Cephalometry</topic><topic>Cervical intraepithelial neoplasia</topic><topic>Cervical Intraepithelial Neoplasia - pathology</topic><topic>Cervical Intraepithelial Neoplasia - surgery</topic><topic>conisation</topic><topic>Conization - adverse effects</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Head - anatomy & histology</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Obstetric Labor, Premature - etiology</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>prematurity</topic><topic>Retrospective Studies</topic><topic>Sexual Behavior - statistics & numerical data</topic><topic>Uterine Cervical Neoplasms - pathology</topic><topic>Uterine Cervical Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van de Vijver, A</creatorcontrib><creatorcontrib>Poppe, W</creatorcontrib><creatorcontrib>Verguts, J</creatorcontrib><creatorcontrib>Arbyn, M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van de Vijver, A</au><au>Poppe, W</au><au>Verguts, J</au><au>Arbyn, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital</atitle><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle><addtitle>BJOG</addtitle><date>2010-02</date><risdate>2010</risdate><volume>117</volume><issue>3</issue><spage>268</spage><epage>273</epage><pages>268-273</pages><issn>1470-0328</issn><eissn>1471-0528</eissn><abstract>Please cite this paper as: van de Vijver A, Poppe W, Verguts J, Arbyn M. Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital. BJOG 2010;117:268–273.
Objective To assess pregnancy outcome after conisation.
Design Retrospective cohort study.
Setting Belgium, data from a university hospital.
Population Fifty‐five pregnancies in 34 women after conisation, and 55 pregnancies in 54 women without a history of conisation or cervical intraepithelial neoplasia (CIN).
Methods Hospital data were reviewed and questionnaires were collected from 599 women who had a conisation in a 5‐year period, among whom subsequent pregnancies were identified. The control group consisted of matched pregnancies of women without a history of conisation.
Main outcome measures Gestational age at delivery, neonatal biometry, neonatal condition at birth.
Results Numbers of sexual partners (4.6 ± 3.4 SD versus 2.5 ± 2.5 SD) and ex‐smokers were significantly higher in the study group compared with the control group. Gestational age at delivery (266 ± 2 days versus 274 ± 9 days), neonatal head circumference (33.9 ± 2.5 cm, versus 34.6 ± 2.5 cm) and birthweight (3088 ± 754 g versus 3381 ± 430 g) were significantly lower in the study group compared with the control group. Numbers of preterm [<37 weeks; 14/55 (25%) versus 2/55 (4%); P = 0.002] and severe preterm (<34 weeks; 6/55 (11%) versus 0/55 (0%); P = 0.031] deliveries in the study group were significantly higher. There were no cases of perinatal mortality.
Conclusions Conisation affects obstetrical outcome after conisation for CIN. Babies tend to be born earlier and are smaller. It is not clear whether this is related to the procedure or to factors linked with CIN.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19943824</pmid><doi>10.1111/j.1471-0528.2009.02437.x</doi><tpages>6</tpages></addata></record> |
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| subjects | Biological and medical sciences Birth Weight Cephalometry Cervical intraepithelial neoplasia Cervical Intraepithelial Neoplasia - pathology Cervical Intraepithelial Neoplasia - surgery conisation Conization - adverse effects Female Gestational Age Gynecology. Andrology. Obstetrics Head - anatomy & histology Humans Infant, Newborn Male Medical sciences Obstetric Labor, Premature - etiology Pregnancy Pregnancy Outcome prematurity Retrospective Studies Sexual Behavior - statistics & numerical data Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - surgery |
| title | Pregnancy outcome after cervical conisation: a retrospective cohort study in the Leuven University Hospital |
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