Increased Level of Arginase Activity Correlates with Disease Severity in HIV-Seropositive Patients

Infection with human immunodeficiency virus (HIV) results in a chronic infection that progressively impairs the immune system. Although depletion of CD4+ T cells is frequently used to explain immunosuppression, chronicity of infection and progressive loss of CD4+ T cells are not sufficient to fully...

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Veröffentlicht in:	The Journal of infectious diseases 2010-08, Vol.202 (3), p.374-385
Hauptverfasser:	Cloke, T. E., Garvey, L., Choi, B.-S., Abebe, T., Hailu, A., Hancock, M., Kadolsky, U., Bangham, C. R. M., Munder, M., Müller, I., Taylor, G. P., Kropf, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arginase - metabolism Biological and medical sciences Blood CD4 Lymphocyte Count Cells, Cultured Correlations Female Fundamental and applied biological sciences. Psychology Granulocytes HIV HIV - isolation & purification HIV Infections - immunology HIV Infections - pathology HIV/AIDS Human viral diseases Humans Infectious diseases Leukocytes, Mononuclear - enzymology Male Medical sciences Microbiology Middle Aged Myeloid cells Neutrophils P values Severity of Illness Index Statistical significance T lymphocytes Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load
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