Inhibition of L-Type Amino Acid Transporter Modulates the Expression of Cell Cycle Regulatory Factors in KB Oral Cancer Cells

The purpose of this study was to examine the effect of 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH), an inhibitor of L-type amino acid transporters, on the cell growth suppression in KB human oral cancer cells and to study the roles of cell cycle regulatory factors in the BCH-induced growt...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2010/07/01, Vol.33(7), pp.1117-1121
Hauptverfasser:	Kim, Chun Sung, Moon, In-Sung, Park, Ju-Hyun, Shin, Woo-Cheol, Chun, Hong Sung, Lee, Sook-Young, Kook, Joong-Ki, Kim, Heung-Joong, Park, Joo-Cheol, Endou, Hitoshi, Kanai, Yoshikatsu, Lee, Byung-Kwon, Kim, Do Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid Amino Acid Transport Systems - antagonists & inhibitors Blotting, Western cancer cell Cell Cycle Proteins - physiology cell cycle regulatory factor Cell Line, Tumor Humans Immunoprecipitation L-type amino acid transporter Mouth Neoplasms - pathology
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