Self-Assembled TiO₂ Nanocrystal Clusters for Selective Enrichment of Intact Phosphorylated Proteins

Self-Assembled TiO₂ Nanocrystal Clusters for Selective Enrichment of Intact Phosphorylated Proteins

Mesoporous traps: The title clusters were fabricated through self‐assembly of nanocrystals in emulsion droplets and subsequent protective calcination. The specific affinity offered by the metal oxide and the size‐exclusion mechanism enabled by the mesoporous structure enable the use of these cluster...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2010-03, Vol.49 (10), p.1862-1866
Hauptverfasser: Lu, Zhenda, Ye, Miaomiao, Li, Ni, Zhong, Wenwan, Yin, Yadong
Format: Artikel
Sprache:eng
Schlagworte:
mesoporous materials
Microscopy, Electron, Transmission
Models, Molecular
nanoparticles
Nanoparticles - chemistry
Phosphorylation
Porosity
proteins
Proteins - chemistry
self-assembly
titanium
Titanium - chemistry
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Beschreibung
Zusammenfassung:Mesoporous traps: The title clusters were fabricated through self‐assembly of nanocrystals in emulsion droplets and subsequent protective calcination. The specific affinity offered by the metal oxide and the size‐exclusion mechanism enabled by the mesoporous structure enable the use of these clusters for efficient enrichment of intact phosphorylated proteins from complex biological samples (see picture).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200906648