DNA-protein binding rates: Bending fluctuation and hydrodynamic coupling effects

We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory focuses on two competing effects: polymer shape fluctuations, whi...

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Veröffentlicht in:	The Journal of chemical physics 2010-04, Vol.132 (13), p.135103-135103-13
Hauptverfasser:	von Hansen, Yann, Netz, Roland R., Hinczewski, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytoskeleton - chemistry Cytoskeleton - metabolism Diffusion DNA - chemistry DNA - metabolism Kinetics Models, Chemical Molecular Conformation Molecular Dynamics Simulation Movement Polymers - chemistry Polymers - metabolism Protein Binding Proteins - chemistry Proteins - metabolism
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