Effects of low doses of hydrochloride tetracycline on bone metabolism and uterus in ovariectomized rats

AIM:To study the effects of low doses of hydrochloride tetracycline (Tc) on bone metabolism and uterus in the ovariectomized (Ova) rats. METHODS:Forty 3-month-old rats were randomly divided into 5 groups: sham group, Ova group, Tc1 group (1.2mg·kg^-1·d^-1), Tc2 group (4.8mg·kg^-1·d^-1), and estrone...

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Veröffentlicht in:	Acta pharmacologica Sinica 2003-06, Vol.24 (6), p.599-604
Hauptverfasser:	Li, Qing-Nan, Hu, Bin, Huang, Lian-Fang, Chen, Yan, Weng, Ling-Ling, Zheng, Hu, Chen, Huai-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Resorption Estrone - pharmacology Female Organ Size - drug effects Ovariectomy Protein Synthesis Inhibitors - administration & dosage Protein Synthesis Inhibitors - pharmacology Random Allocation Rats Rats, Sprague-Dawley Tetracycline - administration & dosage Tetracycline - pharmacology Tibia - drug effects Tibia - metabolism Uterus - drug effects Uterus - pathology 动物实验卵巢切除四环素药物代谢
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