Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

Recognition of apoptotic cells by phagocytes is not fully understood. In C. elegans , the transthyretin-like protein, TTR-52, is secreted by the endoderm and clusters around apoptotic cells, inducing their engulfment through the CED-1/6/7 pathway. During apoptosis, dying cells are swiftly removed by...

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