Effects of the LHRH antagonist Cetrorelix on affective and cognitive functions in rats

The decapeptide LHRH antagonist, Cetrorelix, inhibits gonadotropin and sex-steroid secretion. Cetrorelix is used for IVF-ET procedures and for the treatment of benign prostatic hyperplasia, endometriosis and leiomyomas. However little is known about the effects of Cetrorelix on brain functions. Prev...

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Veröffentlicht in:	Regulatory peptides 2010-01, Vol.159 (1), p.142-147
Hauptverfasser:	Telegdy, G., Adamik, A., Tanaka, M., Schally, A.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Anxiety Agents - pharmacology Antidepressive Antidepressive Agents - pharmacology Anxiolytic Biological and medical sciences Cetrorelix Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Gonadotropin-Releasing Hormone - analogs & derivatives Gonadotropin-Releasing Hormone - antagonists & inhibitors Gonadotropin-Releasing Hormone - pharmacology Hormone Antagonists - pharmacology Male Maze Learning - drug effects Medical sciences Memory correction Mice Neuropharmacology Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Rats, Wistar Vertebrates: endocrinology
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