The Association between Cigarette Smoking and Risk of Colorectal Cancer in a Large Prospective Cohort from the United States

Background: Many studies have reported a 20% to 60% increase in risk of colorectal cancer associated with active smoking. However, neither the U.S. Surgeon General nor the IARC have classified the relationship as causal because of concern about residual confounding. Methods: In a prospective study o...

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