An Evaluation of an Adapted U.S. Model of Pharmaceutical Care to Improve Psychoactive Prescribing for Nursing Home Residents in Northern Ireland (Fleetwood Northern Ireland Study)
OBJECTIVES: To test the effect of an adapted U.S. model of pharmaceutical care on prescribing of inappropriate psychoactive (anxiolytic, hypnotic, and antipsychotic) medications and falls in nursing homes for older people in Northern Ireland (NI). DESIGN: Cluster randomized controlled trial. SETTING...
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| Veröffentlicht in: | Journal of the American Geriatrics Society (JAGS) 2010-01, Vol.58 (1), p.44-53 |
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| container_title | Journal of the American Geriatrics Society (JAGS) |
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| creator | Patterson, Susan M. Hughes, Carmel M. Crealey, Grainne Cardwell, Chris Lapane, Kate L. |
| description | OBJECTIVES: To test the effect of an adapted U.S. model of pharmaceutical care on prescribing of inappropriate psychoactive (anxiolytic, hypnotic, and antipsychotic) medications and falls in nursing homes for older people in Northern Ireland (NI).
DESIGN: Cluster randomized controlled trial.
SETTING: Nursing homes randomized to intervention (receipt of the adapted model of care; n=11) or control (usual care continued; n=11).
PARTICIPANTS: Residents aged 65 and older who provided informed consent (N=334; 173 intervention, 161 control).
INTERVENTION: Specially trained pharmacists visited intervention homes monthly for 12 months and reviewed residents' clinical and prescribing information, applied an algorithm that guided them in assessing the appropriateness of psychoactive medication, and worked with prescribers (general practitioners) to improve the prescribing of these drugs. The control homes received usual care.
MEASUREMENTS: The primary end point was the proportion of residents prescribed one or more inappropriate psychoactive medicine according to standardized protocols; falls were evaluated using routinely collected falls data mandated by the regulatory body for nursing homes in NI.
RESULTS: The proportion of residents taking inappropriate psychoactive medications at 12 months in the intervention homes (25/128, 19.5%) was much lower than in the control homes (62/124, 50.0%) (odds ratio=0.26, 95% confidence interval=0.14–0.49) after adjustment for clustering within homes. No differences were observed at 12 months in the falls rate between the intervention and control groups.
CONCLUSION: Marked reductions in inappropriate psychoactive medication prescribing in residents resulted from pharmacist review of targeted medications, but there was no effect on falls. |
| doi_str_mv | 10.1111/j.1532-5415.2009.02617.x |
| format | Article |
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DESIGN: Cluster randomized controlled trial.
SETTING: Nursing homes randomized to intervention (receipt of the adapted model of care; n=11) or control (usual care continued; n=11).
PARTICIPANTS: Residents aged 65 and older who provided informed consent (N=334; 173 intervention, 161 control).
INTERVENTION: Specially trained pharmacists visited intervention homes monthly for 12 months and reviewed residents' clinical and prescribing information, applied an algorithm that guided them in assessing the appropriateness of psychoactive medication, and worked with prescribers (general practitioners) to improve the prescribing of these drugs. The control homes received usual care.
MEASUREMENTS: The primary end point was the proportion of residents prescribed one or more inappropriate psychoactive medicine according to standardized protocols; falls were evaluated using routinely collected falls data mandated by the regulatory body for nursing homes in NI.
RESULTS: The proportion of residents taking inappropriate psychoactive medications at 12 months in the intervention homes (25/128, 19.5%) was much lower than in the control homes (62/124, 50.0%) (odds ratio=0.26, 95% confidence interval=0.14–0.49) after adjustment for clustering within homes. No differences were observed at 12 months in the falls rate between the intervention and control groups.
CONCLUSION: Marked reductions in inappropriate psychoactive medication prescribing in residents resulted from pharmacist review of targeted medications, but there was no effect on falls.</description><identifier>ISSN: 0002-8614</identifier><identifier>EISSN: 1532-5415</identifier><identifier>DOI: 10.1111/j.1532-5415.2009.02617.x</identifier><identifier>PMID: 20002510</identifier><identifier>CODEN: JAGSAF</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Aged, 80 and over ; Algorithms ; Biological and medical sciences ; Clinical trials ; cluster randomized controlled trial ; Drug Prescriptions - standards ; Drug therapy ; Falls ; Female ; General aspects ; Humans ; Intervention ; Male ; Medical sciences ; Miscellaneous ; Models, Theoretical ; Northern Ireland ; Nursing Homes ; pharmaceutical care ; psychoactive medication ; Psychotropic drugs ; Psychotropic Drugs - therapeutic use ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Single-Blind Method ; United States</subject><ispartof>Journal of the American Geriatrics Society (JAGS), 2010-01, Vol.58 (1), p.44-53</ispartof><rights>2009, Copyright the Authors. Journal compilation © 2009, The American Geriatrics Society</rights><rights>2015 INIST-CNRS</rights><rights>Journal compilation 2010 The American Geriatrics Society/Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4637-aa1d1c85d513fcfdd0e09d7e90774de99294eb8995047ceb49087c1ccaa655e63</citedby><cites>FETCH-LOGICAL-c4637-aa1d1c85d513fcfdd0e09d7e90774de99294eb8995047ceb49087c1ccaa655e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1532-5415.2009.02617.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1532-5415.2009.02617.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,4024,27923,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22314622$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20002510$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patterson, Susan M.</creatorcontrib><creatorcontrib>Hughes, Carmel M.</creatorcontrib><creatorcontrib>Crealey, Grainne</creatorcontrib><creatorcontrib>Cardwell, Chris</creatorcontrib><creatorcontrib>Lapane, Kate L.</creatorcontrib><title>An Evaluation of an Adapted U.S. Model of Pharmaceutical Care to Improve Psychoactive Prescribing for Nursing Home Residents in Northern Ireland (Fleetwood Northern Ireland Study)</title><title>Journal of the American Geriatrics Society (JAGS)</title><addtitle>J Am Geriatr Soc</addtitle><description>OBJECTIVES: To test the effect of an adapted U.S. model of pharmaceutical care on prescribing of inappropriate psychoactive (anxiolytic, hypnotic, and antipsychotic) medications and falls in nursing homes for older people in Northern Ireland (NI).
DESIGN: Cluster randomized controlled trial.
SETTING: Nursing homes randomized to intervention (receipt of the adapted model of care; n=11) or control (usual care continued; n=11).
PARTICIPANTS: Residents aged 65 and older who provided informed consent (N=334; 173 intervention, 161 control).
INTERVENTION: Specially trained pharmacists visited intervention homes monthly for 12 months and reviewed residents' clinical and prescribing information, applied an algorithm that guided them in assessing the appropriateness of psychoactive medication, and worked with prescribers (general practitioners) to improve the prescribing of these drugs. The control homes received usual care.
MEASUREMENTS: The primary end point was the proportion of residents prescribed one or more inappropriate psychoactive medicine according to standardized protocols; falls were evaluated using routinely collected falls data mandated by the regulatory body for nursing homes in NI.
RESULTS: The proportion of residents taking inappropriate psychoactive medications at 12 months in the intervention homes (25/128, 19.5%) was much lower than in the control homes (62/124, 50.0%) (odds ratio=0.26, 95% confidence interval=0.14–0.49) after adjustment for clustering within homes. No differences were observed at 12 months in the falls rate between the intervention and control groups.
CONCLUSION: Marked reductions in inappropriate psychoactive medication prescribing in residents resulted from pharmacist review of targeted medications, but there was no effect on falls.</description><subject>Aged, 80 and over</subject><subject>Algorithms</subject><subject>Biological and medical sciences</subject><subject>Clinical trials</subject><subject>cluster randomized controlled trial</subject><subject>Drug Prescriptions - standards</subject><subject>Drug therapy</subject><subject>Falls</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Intervention</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Models, Theoretical</subject><subject>Northern Ireland</subject><subject>Nursing Homes</subject><subject>pharmaceutical care</subject><subject>psychoactive medication</subject><subject>Psychotropic drugs</subject><subject>Psychotropic Drugs - therapeutic use</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Single-Blind Method</subject><subject>United States</subject><issn>0002-8614</issn><issn>1532-5415</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcGO0zAQhiMEYkvhFZCFhIBDg53EcXzgUJXdbqFbVpQVR8u1J9TdJC62s9s-Fy9IQkuR4IIP9lj_949m9EcRIjgm3Xm7iQlNkxHNCI0TjHmMk5ywePcgGpyEh9EAY5yMipxkZ9ET7zcYkwQXxePoLOkVSvAg-jFu0PmdrFoZjG2QLZFs0FjLbQCNbuJljK6shqoXrtfS1VJBG4ySFZpIByhYNKu3zt4BuvZ7tbZSBdN_HHjlzMo031BpHVq0zvf1pa0BfQZvNDTBI9OghXVhDa5BMweVbDR6fVEBhHtr9b_aMrR6_-Zp9KiUlYdnx3cY3Vycf5lcjuafprPJeD5SWZ6ykZREE1VQTUlaqlJrDJhrBhwzlmngPOEZrArOKc6YglXGccEUUUrKnFLI02H06tC3W_B7Cz6I2ngFVTcK2NYLlqY5KRjlHfniL3JjW9d0w4mE4JTxjBUdVBwg5az3DkqxdaaWbi8IFn2sYiP69ESfnuhjFb9iFbvO-vzYv13VoE_G3zl2wMsjIH0XTulko4z_wyUpyfLuHkbvDty9qWD_3wOID9NlX3X-0cFvfIDdyS_drchZyqj4upgKkl2l-Xv8UczTnx7Kza0</recordid><startdate>201001</startdate><enddate>201001</enddate><creator>Patterson, Susan M.</creator><creator>Hughes, Carmel M.</creator><creator>Crealey, Grainne</creator><creator>Cardwell, Chris</creator><creator>Lapane, Kate L.</creator><general>Blackwell Publishing Inc</general><general>Wiley-Blackwell</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201001</creationdate><title>An Evaluation of an Adapted U.S. Model of Pharmaceutical Care to Improve Psychoactive Prescribing for Nursing Home Residents in Northern Ireland (Fleetwood Northern Ireland Study)</title><author>Patterson, Susan M. ; Hughes, Carmel M. ; Crealey, Grainne ; Cardwell, Chris ; Lapane, Kate L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4637-aa1d1c85d513fcfdd0e09d7e90774de99294eb8995047ceb49087c1ccaa655e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Aged, 80 and over</topic><topic>Algorithms</topic><topic>Biological and medical sciences</topic><topic>Clinical trials</topic><topic>cluster randomized controlled trial</topic><topic>Drug Prescriptions - standards</topic><topic>Drug therapy</topic><topic>Falls</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Intervention</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Models, Theoretical</topic><topic>Northern Ireland</topic><topic>Nursing Homes</topic><topic>pharmaceutical care</topic><topic>psychoactive medication</topic><topic>Psychotropic drugs</topic><topic>Psychotropic Drugs - therapeutic use</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Single-Blind Method</topic><topic>United States</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patterson, Susan M.</creatorcontrib><creatorcontrib>Hughes, Carmel M.</creatorcontrib><creatorcontrib>Crealey, Grainne</creatorcontrib><creatorcontrib>Cardwell, Chris</creatorcontrib><creatorcontrib>Lapane, Kate L.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Geriatrics Society (JAGS)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patterson, Susan M.</au><au>Hughes, Carmel M.</au><au>Crealey, Grainne</au><au>Cardwell, Chris</au><au>Lapane, Kate L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Evaluation of an Adapted U.S. Model of Pharmaceutical Care to Improve Psychoactive Prescribing for Nursing Home Residents in Northern Ireland (Fleetwood Northern Ireland Study)</atitle><jtitle>Journal of the American Geriatrics Society (JAGS)</jtitle><addtitle>J Am Geriatr Soc</addtitle><date>2010-01</date><risdate>2010</risdate><volume>58</volume><issue>1</issue><spage>44</spage><epage>53</epage><pages>44-53</pages><issn>0002-8614</issn><eissn>1532-5415</eissn><coden>JAGSAF</coden><abstract>OBJECTIVES: To test the effect of an adapted U.S. model of pharmaceutical care on prescribing of inappropriate psychoactive (anxiolytic, hypnotic, and antipsychotic) medications and falls in nursing homes for older people in Northern Ireland (NI).
DESIGN: Cluster randomized controlled trial.
SETTING: Nursing homes randomized to intervention (receipt of the adapted model of care; n=11) or control (usual care continued; n=11).
PARTICIPANTS: Residents aged 65 and older who provided informed consent (N=334; 173 intervention, 161 control).
INTERVENTION: Specially trained pharmacists visited intervention homes monthly for 12 months and reviewed residents' clinical and prescribing information, applied an algorithm that guided them in assessing the appropriateness of psychoactive medication, and worked with prescribers (general practitioners) to improve the prescribing of these drugs. The control homes received usual care.
MEASUREMENTS: The primary end point was the proportion of residents prescribed one or more inappropriate psychoactive medicine according to standardized protocols; falls were evaluated using routinely collected falls data mandated by the regulatory body for nursing homes in NI.
RESULTS: The proportion of residents taking inappropriate psychoactive medications at 12 months in the intervention homes (25/128, 19.5%) was much lower than in the control homes (62/124, 50.0%) (odds ratio=0.26, 95% confidence interval=0.14–0.49) after adjustment for clustering within homes. No differences were observed at 12 months in the falls rate between the intervention and control groups.
CONCLUSION: Marked reductions in inappropriate psychoactive medication prescribing in residents resulted from pharmacist review of targeted medications, but there was no effect on falls.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>20002510</pmid><doi>10.1111/j.1532-5415.2009.02617.x</doi><tpages>10</tpages></addata></record> |
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| ispartof | Journal of the American Geriatrics Society (JAGS), 2010-01, Vol.58 (1), p.44-53 |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Aged, 80 and over Algorithms Biological and medical sciences Clinical trials cluster randomized controlled trial Drug Prescriptions - standards Drug therapy Falls Female General aspects Humans Intervention Male Medical sciences Miscellaneous Models, Theoretical Northern Ireland Nursing Homes pharmaceutical care psychoactive medication Psychotropic drugs Psychotropic Drugs - therapeutic use Public health. Hygiene Public health. Hygiene-occupational medicine Single-Blind Method United States |
| title | An Evaluation of an Adapted U.S. Model of Pharmaceutical Care to Improve Psychoactive Prescribing for Nursing Home Residents in Northern Ireland (Fleetwood Northern Ireland Study) |
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